[HTML][HTML] Dysfunctional purinergic signaling correlates with disease severity in COVID-19 patients
AJ Pietrobon, R Andrejew, RWA Custódio… - Frontiers in …, 2022 - frontiersin.org
Ectonucleotidases modulate inflammatory responses by balancing extracellular ATP and
adenosine (ADO) and might be involved in COVID-19 immunopathogenesis. Here, we …
adenosine (ADO) and might be involved in COVID-19 immunopathogenesis. Here, we …
[HTML][HTML] Low level laser therapy reduces acute lung inflammation in a model of pulmonary and extrapulmonary LPS-induced ARDS
…, NC Rigonato-Oliveira, RWA Custódio… - … of Photochemistry and …, 2014 - Elsevier
The present study aimed to investigate the effects low level laser therapy (LLLT) in a LPS-induced
pulmonary and extrapulmonary acute respiratory distress syndrome (ARDS) in BALB/…
pulmonary and extrapulmonary acute respiratory distress syndrome (ARDS) in BALB/…
[HTML][HTML] CpG-ODN shapes alum adjuvant activity signaling via MyD88 and IL-10
Aluminum-containing adjuvants usually referred as Alum are considered as T helper type-2 (Th2)
adjuvants, while agonists of toll-like receptors (TLRs) are viewed as adjuvants that …
adjuvants, while agonists of toll-like receptors (TLRs) are viewed as adjuvants that …
[HTML][HTML] Allergen-specific immunotherapy with liposome containing CpG-ODN in murine model of asthma relies on MyD88 signaling in dendritic cells
Changing the immune responses to allergens is the cornerstone of allergen immunotherapy.
Allergen-specific immunotherapy that consists of repeated administration of increasing …
Allergen-specific immunotherapy that consists of repeated administration of increasing …
[HTML][HTML] Aerobic exercise reduces asthma phenotype by modulation of the leukotriene pathway
RW Alberca-Custódio, FR Greiffo… - Frontiers in …, 2016 - frontiersin.org
Introduction Leukotrienes (LTs) play a central role in asthma. Low- to moderate-intensity
aerobic exercise (AE) reduces asthmatic inflammation in clinical studies and in experimental …
aerobic exercise (AE) reduces asthmatic inflammation in clinical studies and in experimental …
[HTML][HTML] Imbalanced IL-1B and IL-18 Expression in Sézary Syndrome
…, D Miyashiro, FME Teixeira, RWA Custódio… - International Journal of …, 2023 - mdpi.com
Sézary syndrome (SS) is a rare and aggressive type of cutaneous T-cell lymphoma, with an
abnormal inflammatory response in affected skin. The cytokines IL-1B and IL-18, as key …
abnormal inflammatory response in affected skin. The cytokines IL-1B and IL-18, as key …
Aerobic training inhibits bleomycin-induced pulmonary fibrosis in BALB/c mice
…, M Oliveira-Junior, RW Custodio… - European …, 2014 - Eur Respiratory Soc
Idiopatic pulmonary fibrosis (IPF) is a devastating disease with poor prognostic and no effective
treatment is available. Although there are a considerable number of studies showing that …
treatment is available. Although there are a considerable number of studies showing that …
Infection-elicited microbiota promotes host adaptation to nutrient restriction
…, R Wesley Alberca-Custodio… - Proceedings of the …, 2023 - National Acad Sciences
The microbiota performs multiple functions vital to host fitness, including defense against
pathogens and adaptation to dietary changes. Yet, how environmental challenges shape …
pathogens and adaptation to dietary changes. Yet, how environmental challenges shape …
TLR9 agonist adsorbed to alum adjuvant prevents asthma-like responses induced by Blomia tropicalis mite extract
FPB Nunes, RW Alberca-Custódio… - Journal of Leukocyte …, 2019 - academic.oup.com
Blomia tropicalis mite is highly prevalent in tropical and subtropical regions and it is associated
with allergic diseases such as rhinitis and asthma. By using an OVA-model of allergic …
with allergic diseases such as rhinitis and asthma. By using an OVA-model of allergic …
aerobic exercise reduces asthma Phenotype by Modulation of the leukotriene Pathway
RWA Custódio, FR Greiffo, BA MacKenzie… - 2016 - arca.fiocruz.br
Leukotrienes (LTs) play a central role in asthma. Low-to moderate-intensity aerobic exercise
(AE) reduces asthmatic inflammation in clinical studies and in experimental models. This …
(AE) reduces asthmatic inflammation in clinical studies and in experimental models. This …