Cytochromes P450 in phenolic metabolism
J Ehlting, B Hamberger, R Million-Rousseau… - Phytochemistry …, 2006 - Springer
Three independent cytochrome P450 enzyme families catalyze the three rate-limiting
hydroxylation steps in the phenylpropanoid pathway leading to the biosynthesis of lignin and …
hydroxylation steps in the phenylpropanoid pathway leading to the biosynthesis of lignin and …
Macitentan for the treatment of idiopathic pulmonary fibrosis: the randomised controlled MUSIC trial
G Raghu, R Million-Rousseau… - European …, 2013 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis is a progressive, fatal disease. This prospective, randomised,
double-blind, multicentre, parallel-group, placebo-controlled phase II trial ( NCT00903331 ) …
double-blind, multicentre, parallel-group, placebo-controlled phase II trial ( NCT00903331 ) …
Functional characterization of two p-coumaroyl ester 3′-hydroxylase genes from coffee tree: evidence of a candidate for chlorogenic acid biosynthesis
V Mahesh, R Million-Rousseau, P Ullmann… - Plant Molecular …, 2007 - Springer
Chlorogenic acid (5-CQA) is one of the major soluble phenolic compounds that is accumulated
in coffee green beans. With other hydroxycinnamoyl quinic acids (HQAs), this compound …
in coffee green beans. With other hydroxycinnamoyl quinic acids (HQAs), this compound …
Efficacy and safety of macitentan in idiopathic pulmonary fibrosis: results of a prospective, randomized, double-blind, placebo-controlled trial
G Raghu, R Million-Rousseau, A Morganti… - … CLINICAL TRIALS IN …, 2012 - atsjournals.org
METHODS: The prospective, multicenter, randomized, double-blind, parallel-group, placebo-controlled,
acitentan e in an diopathic M US I pulmonary fibrosis linical (MUSIC) trial …
acitentan e in an diopathic M US I pulmonary fibrosis linical (MUSIC) trial …
MUSIC: Efficacy and safety of macitentan in idiopathic pulmonary fibrosis (IPF)
J Behr, R Million-Rousseau, A Morganti, L Perchenet… - 2012 - Eur Respiratory Soc
Endothelin-1 may contribute to IPF pathophysiology. The prospective double-blind Macitentan
USe in an IPF Clinical (MUSIC) trial (NCT00903331) investigated the endothelin receptor …
USe in an IPF Clinical (MUSIC) trial (NCT00903331) investigated the endothelin receptor …
[HTML][HTML] A 13C isotope labeling method for the measurement of lignin metabolic flux in Arabidopsis stems
Background Metabolic fluxes represent the functional phenotypes of biochemical pathways
and are essential to reveal the distribution of precursors among metabolic networks. …
and are essential to reveal the distribution of precursors among metabolic networks. …
The safety of new drug treatments for idiopathic pulmonary fibrosis
S Fletcher, MG Jones, K Spinks, G Sgalla… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: The management of idiopathic pulmonary fibrosis (IPF) has been transformed
by the recent approval of two anti-fibrotic drugs, nintedanib and pirfenidone. An increasing …
by the recent approval of two anti-fibrotic drugs, nintedanib and pirfenidone. An increasing …
[HTML][HTML] Idiopathic interstitial pneumonia-associated pulmonary hypertension: A target for therapy?
Advances in the treatment of idiopathic interstitial pneumonia (IIP) represent an urgent,
unmet medical need for patients with this category of diffuse parenchymal lung disease. IIPs …
unmet medical need for patients with this category of diffuse parenchymal lung disease. IIPs …
Significance of autoimmune disease in severe pulmonary hypertension complicating extensive pulmonary fibrosis: A prospective cohort study
The association of autoimmune disease (AI) with transplant-free survival in the setting of severe
Group 3 pulmonary hypertension and extensive pulmonary fibrosis remains unclear. We …
Group 3 pulmonary hypertension and extensive pulmonary fibrosis remains unclear. We …
[BOOK][B] Qualitative structure-activity relationship (QSAR) studies of 3, 5-dicaffeoylquinic acid geometrical isomers with the aid of density functional theory (DFT), liquid …
MM Makola - 2016 - search.proquest.com
Till now, metabolite identification from complex mixtures remains the most difficult step
during metabolomics studies. This is mainly due to the presence of structurally diverse and …
during metabolomics studies. This is mainly due to the presence of structurally diverse and …