Tertiary motifs in RNA structure and folding
RT Batey, RP Rambo… - Angewandte Chemie …, 1999 - Wiley Online Library
… The GNRA sequence motif, in which any nucleotide is accommodated in the second position
and the third position is a purine base (R ŕ A or G), is the most prevalent tetraloop motif in …
and the third position is a purine base (R ŕ A or G), is the most prevalent tetraloop motif in …
Super-resolution in solution X-ray scattering and its applications to structural systems biology
RP Rambo, JA Tainer - Annual review of biophysics, 2013 - annualreviews.org
… Similarly, a comparison of the protein's R g to Flory's … , to R g RC for a random coil) can be
used to infer flexibility (12, 78). An R g < R g RC suggests compactness and likewise R g > R g …
used to infer flexibility (12, 78). An R g < R g RC suggests compactness and likewise R g > R g …
Bridging the solution divide: comprehensive structural analyses of dynamic RNA, DNA, and protein assemblies by small-angle X-ray scattering
RP Rambo, JA Tainer - Current opinion in structural biology, 2010 - Elsevier
… estimation of the radius-of-gyration (R g ) within the Guinier region of the data (q·R g … R g
describes the mass distribution of a macromolecule about its center of gravity. An increase in R …
describes the mass distribution of a macromolecule about its center of gravity. An increase in R …
Accurate assessment of mass, models and resolution by small-angle scattering
RP Rambo, JA Tainer - Nature, 2013 - nature.com
… We discovered that a parameter, Q R , defined as the ratio of the square of V c to R g with
units of Ĺ 3 , is linear versus molecular mass in a log–log plot (Figs 2, 3 and Supplementary Fig…
units of Ĺ 3 , is linear versus molecular mass in a log–log plot (Figs 2, 3 and Supplementary Fig…
Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS)
GL Hura, AL Menon, M Hammel, RP Rambo… - Nature …, 2009 - nature.com
… with R G > 75 Ĺ and a longest dimension across the molecule (D max ) of at least 340 Ĺ (larger
than a ribosome). Scattering curve oscillations beyond q > 0.1 Ĺ −1 with such a large R G …
than a ribosome). Scattering curve oscillations beyond q > 0.1 Ĺ −1 with such a large R G …
Structural mechanism of abscisic acid binding and signaling by dimeric PYR1
N Nishimura, K Hitomi, AS Arvai, RP Rambo, C Hitomi… - Science, 2009 - science.org
The phytohormone abscisic acid (ABA) acts in seed dormancy, plant development, drought
tolerance, and adaptive responses to environmental stresses. Structural mechanisms …
tolerance, and adaptive responses to environmental stresses. Structural mechanisms …
Characterizing flexible and intrinsically unstructured biological macromolecules by SAS using the Porod‐Debye law
RP Rambo, JA Tainer - Biopolymers, 2011 - Wiley Online Library
… This method normalizes the scattering data to I(0) and skews the scattering angle by R g (Figure
3C), such that the resulting SAS data in a Kratky plot is normalized for c, V, and R g …
3C), such that the resulting SAS data in a Kratky plot is normalized for c, V, and R g …
Crystal structure of the ribonucleoprotein core of the signal recognition particle
… Using diffraction data extending from 30.0 to 1.8 Å resolution, a model of the complex was
built and refined to a crystallographic R factor of 19.9% and a freeR factor of 22.1% (Table 1). …
built and refined to a crystallographic R factor of 19.9% and a freeR factor of 22.1% (Table 1). …
Structural basis of Smoothened regulation by its extracellular domains
… either CRD–linker domain contacts or the linker domain itself increases the constitutive
activity of SMO, implicating these regions in stabilizing an inactive state, analogous to the D(E)R …
activity of SMO, implicating these regions in stabilizing an inactive state, analogous to the D(E)R …
SMARCAL1 catalyzes fork regression and Holliday junction migration to maintain genome stability during DNA replication
R Bétous, AC Mason, RP Rambo… - Genes & …, 2012 - genesdev.cshlp.org
… The radius of gyration (r g ) obtained from the Guinier region was 33.0 ± 0.3 Ĺ (…
compared with glucose isomerase, a spherical protein at 173 kDa with a similar R g of 32 Ĺ. …
compared with glucose isomerase, a spherical protein at 173 kDa with a similar R g of 32 Ĺ. …