[HTML][HTML] Insights into immunothrombotic mechanisms in acute stroke due to vaccine-induced immune thrombotic thrombocytopenia

…, T Baumann, C Werlein, L Fingerhut, R Imker… - Frontiers in …, 2022 - frontiersin.org
During the COVID-19 pandemic, vaccination is the most important countermeasure.
Pharmacovigilance concerns however emerged with very rare, but potentially disastrous thrombotic …

Characterization of Tailor-Made Copolymers of Oligo(ethylene glycol) Methyl Ether Methacrylate and N,N-Dimethylaminoethyl Methacrylate as Nonviral Gene …

…, MM Golas, B Sander, H Stark, R Imker… - …, 2010 - ACS Publications
Oligo(ethylene glycol) methyl ether methacrylates (OEGMA) of various chain lengths (ie, 9,
23, or 45 EG units) and N,N-dimethylaminoethyl methacrylate (DMAEMA) were …

Endogenous deoxyribonuclease activity and cell-free deoxyribonucleic acid in acute ischemic stroke: a cohort study

…, H Worthmann, R Lichtinghagen, R Imker… - Stroke, 2022 - Am Heart Assoc
… A, Heatmap representing Pearson r values of interbiomarker correlations at baseline. B,
Heatmap representing Pearson r values of interbiomarker correlations at 7 d. IFN indicates …

Phage phiC31 integrase‐mediated genomic integration and long‐term gene expression in the lung after nonviral gene delivery

MK Aneja, R Imker, C Rudolph - … for research on the science of …, 2007 - Wiley Online Library
Background Phage ϕC31 integrase has emerged as a potent tool for achieving long‐term
gene expression in different tissues. The present study investigated the activity of ϕC31 …

[HTML][HTML] Methylprednisolone induces extracellular trap formation and enhances bactericidal effect of canine neutrophils

N Steffensen, R Imker, S Lassnig, M Fulde… - International journal of …, 2021 - mdpi.com
Methylprednisolone is a glucocorticoid and can negatively influence immune defense
mechanisms. During bacterial infections in the dog, neutrophils infiltrate infected tissue and …

[HTML][HTML] Impact of bronchoalveolar lavage from influenza A virus diseased pigs on neutrophil functions and growth of co-infecting pathogenic bacteria

…, MC Bonilla, M Mörgelin, R Imker… - Frontiers in …, 2024 - frontiersin.org
… Spearman r resulting in a significant negative correlation of cell-free DNA (G), nucleosomes
(H), and H3Cit (J). A simple linear regression is depicted in the graph and the values for r, p, …

[HTML][HTML] Studying the interaction of neutrophils and glaesserella parasuis indicates a serotype independent benefit from degradation of NETs

MC Bonilla, S Lassnig, A Obando Corella, R Imker… - Pathogens, 2022 - mdpi.com
Glaesserella (G.) parasuis is one of the most important porcine pathogens causing Glaesser’s
disease. Neutrophil granulocytes are the major counteracting cell type of the innate …

[HTML][HTML] From Stable to Lab—Investigating Key Factors for Sudden Deaths Caused by Streptococcus suis

I Hennig-Pauka, R Imker, L Mayer, M Brügmann… - Pathogens, 2019 - mdpi.com
Swine stocks are endemically infected with the major porcine pathogen Streptococcus (S.)
suis. The factors governing the transition from colonizing S. suis residing in the tonsils and the …

[HTML][HTML] The effect of doxycycline on canine neutrophil functions

JC Rieder, N Steffensen, R Imker, S Lassnig… - Veterinary Immunology …, 2024 - Elsevier
Doxycycline is a broad-spectrum tetracycline-class antibiotic that is frequently used to treat
bacterial infections. Its use has also been described in immune-mediated diseases due to its …

[HTML][HTML] Optimization of Streptomyces bacteriophage ϕC31 integrase system to prevent post integrative gene silencing in pulmonary type II cells

MK Aneja, J Geiger, R Imker, S Üzgün… - … & Molecular Medicine, 2009 - nature.com
ϕC31 integrase has emerged as a potent tool for achieving long-term gene expression in
different tissues. The present study aimed at optimizing elements of ϕC31 integrase system for …