… This definition of asthma severity works well at the severe end of the spectrum but is less
useful for describing mild asthma (see Topics Requiring Further Research). For example, …

Background: Patients with severe persistent asthma who are inadequately controlled despite
treatment according to current asthma management guidelines have a significant unmet …

Asthma is a complex respiratory disorder characterized by marked heterogeneity in individual
patient disease triggers and response to therapy. Several asthma phenotypes have now …

Background Some patients with severe asthma have recurrent asthma exacerbations
associated with eosinophilic airway inflammation. Early studies suggest that inhibition of …

The clinical benefit and steroid-sparing effect of treatment with the anti-immunoglobulin-E (IgE)
antibody, omalizumab, was assessed in patients with moderate-to-severe allergic asthma…

Background Idiopathic pulmonary fibrosis is a chronic progressive disorder with a poor
prognosis. Methods We conducted a double-blind, randomized, placebo-controlled multicenter …

To find out whether systemic glutathione deficiency is associated with human immunodeficiency
virus (HIV) infection, thus contributing to the immunodeficiency state, glutathione …

Cystic fibrosis (CF), a disorder characterized by mutations of the CF transmembrane regulator
gene, is characterized in the lung by chronic inflammation, leading to progressive damage …

Efficacy and safety of tiotropium+olodaterol fixed-dose combination (FDC) compared with
the mono-components was evaluated in patients with moderate to very severe chronic …

Background Indacaterol is a long-acting inhaled β 2 -agonist (LABA) for the treatment of
chronic obstructive pulmonary disease (COPD). In previous studies, indacaterol provided 24 h …