Mechanisms of the Development of Allergy (MeDALL): Introducing novel concepts in allergy phenotypes

…, M Mäkelä, J Mestres, P Mowinckel, R Nadif… - Journal of Allergy and …, 2017 - Elsevier
Asthma, rhinitis, and eczema are complex diseases with multiple genetic and environmental
factors interlinked through IgE-associated and non–IgE-associated mechanisms. …

Worldwide prevalence of rhinitis in adults: a review of definitions and temporal evolution

…, MS Jaakkola, B Jacquemin, R Nadif - Clinical and …, 2022 - Wiley Online Library
… For each definition, we calculated the crude mean, median and confidence intervals based
on binomial distribution with R 4.3. To compare rhinitis prevalence according to different …

Indoor mould exposure, asthma and rhinitis: findings from systematic reviews and recent longitudinal studies

…, B Leynaert, M Keirsbulck, R Nadif - European Respiratory …, 2018 - Eur Respiratory Soc
Starting from the Institute of Medicine (IOM) and World Health Organization (WHO) reports,
this review provides an overview of the literature published from 2006 to 2017 on the …

Adult lung function and long-term air pollution exposure. ESCAPE: a multicentre cohort study and meta-analysis

…, Z Al Kanani, R Nadif, V Siroux, R Hardy… - European respiratory …, 2015 - Eur Respiratory Soc
The chronic impact of ambient air pollutants on lung function in adults is not fully understood.
The objective of this study was to investigate the association of long-term exposure to …

Are allergic multimorbidities and IgE polysensitization associated with the persistence or re‐occurrence of foetal type 2 signalling? The M e DALL hypothesis

…, J Sunyer, J Wright, T Zuberbier, SH Arshad, R Nadif… - Allergy, 2015 - Wiley Online Library
Allergic diseases [asthma, rhinitis and atopic dermatitis (AD)] are complex. They are associated
with allergen‐specific IgE and nonallergic mechanisms that may coexist in the same …

Heterogeneity of asthma according to blood inflammatory patterns

R Nadif, V Siroux, MP Oryszczyn, C Ravault, C Pison… - Thorax, 2009 - thorax.bmj.com
R Nadif1, … Mrs R Nadif, Institut National de la Santé et de la Recherche Médicale, Recherche
en Epidémiologie et Biostatistique U780-IFR69, 16 avenue Paul Vaillant Couturier, 94807 …

Paving the way of systems biology and precision medicine in allergic diseases: the Me DALL success story: Mechanisms of the Development of ALL ergy; EU FP 7‐CP …

…, M Mäkelä, J Mestres, E Minina, P Mowinckel, R Nadif… - Allergy, 2016 - Wiley Online Library
Me DALL (Mechanisms of the Development of ALL ergy; EU FP 7‐ CP ‐ IP ; Project No:
261357; 2010–2015) has proposed an innovative approach to develop early indicators for the …

Association of CAT polymorphisms with catalase activity and exposure to environmental oxidative stimuli

R Nadif, M Mintz, A Jedlicka, JP Bertrand… - Free radical …, 2005 - Taylor & Francis
We tested the hypotheses that catalase activity is modified by CAT single nucleotide
polymorphisms (SNPs) (-262;-844), and by their interactions with oxidant exposures (coal dusts, …

Genome-wide association study of lung function decline in adults with and without asthma

…, JB Wilk, JM Vonk, GA Thun, V Siroux, R Nadif… - Journal of allergy and …, 2012 - Elsevier
BACKGROUND: Genome-wide association studies have identified determinants of chronic
obstructive pulmonary disease, asthma, and lung function level; however, none have …

Air pollution and asthma control in the Epidemiological study on the Genetics and Environment of Asthma

…, J Bousquet, F Gormand, J Just, R Nadif… - J Epidemiol …, 2012 - jech.bmj.com
… (Pearson coefficient r=0.72)… (r=−0.76) and moderately correlated with PM 10 (r=0.45). O
3-an and PM 10 were not correlated (r=−0.08), and O 3-sum and PM 10 were weakly correlated (r