Cellular events that occur in status asthmaticus (SA) remain poorly investigated. Autopsy
studies frequently emphasized about the presence of eosinophils in bronchial airway wall, …

Peroxisome proliferator‐activated receptor γ (PPARγ ), a member of the nuclear receptor
superfamily, has recently been described as a modulator of macrophage functions and as an …

Status asthmaticus (SA) is an acute respiratory failure combining an acute bronchospastic
reaction with a severe airway inflammation. We previously reported an important influx of …

One year after the occurrence of the first case of infection by the Middle East Respiratory
Syndrome coronavirus (MERS-CoV) there is no clear consensus on the best treatment to …

Background: Among factors potentially involved in the increased prevalence of allergic
diseases, modification of the intestinal bacteria flora or lack of bacterial stimulation during …

The late asthmatic reaction (LAR), consecutive to bronchial allergen challenge, is characterized
both by the influx of various cells in proximal and distal airways and by the enhancement …

Invariant natural killer T (iNKT) cells are non-conventional lipid-reactive αβ T lymphocytes
that play a key role in host responses during viral infections, in particular through the swift …

Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor
superfamily. They are divided into three subtypes (α, β or δ, and γ) and are involved in lipid …

BACKGROUND: Airway dendritic cells (DCs) are crucial for allergen-induced sensitization
and inflammation in allergic asthma. After allergen challenge, an increased number of DCs is …

Knockout mice studies have revealed that NF-κB plays a critical role in Th2 cell differentiation
and is therefore required for induction of allergic airway inflammation. However, the …