Background and Methods. The importance of eosinophils in the pathogenesis of bronchial
asthma is not established. In an attempt to evaluate the role of eosinophilic inflammation in …

Nitric oxide (NO) is a mediator of vasodilatation and bronchodilatation synthesised from L-arginine
by the enzyme NO synthase, which is either constitutive or induced by …

Asthma control is improved by combining inhaled corticosteroids with long-acting β 2 -agonists.
However, fluctuating asthma control still occurs. We hypothesized that in patients …

Asthma is a very common chronic disease that occurs in all age groups and is the focus of
various clinical and public health interventions. Both morbidity and mortality from asthma are …

Background: Eosinophils but not neutrophils may play a role in the airway inflammation of
asthma. In chronic bronchitis (CB) and chronic obstructive pulmonary disease (COPD), …

Background: Chronic rhinosinusitis is a common comorbidity of asthma. However, sinonasal
involvement in severe steroid-dependent asthma is still undefined. Objective: The aim of the …

Background: Drug hypersensitivity reactions are common and can be life-threatening.
Confirmation of the diagnosis should be rigorous and based on clinical history and a physical …

Kartagener syndrome (KS) is a trilogy of symptoms (nasal polyps, bronchiectasis, and situs
inversus totalis) that is associated with ultrastructural anomalies of cilia of epithelial cells …

Objective: To determine the ability of montelukast, a leukotriene receptor antagonist, to allow
tapering of inhaled corticosteroids in clinically stable asthmatic patients. Design: Double …

The relationship between asthma and obesity appears to be quite complex. The aim of this
study was to assess the effect of excess weight on asthma control evolution in a cohort of …