Particle size-dependent organ distribution of gold nanoparticles after intravenous administration

WH De Jong, WI Hagens, P Krystek, MC Burger… - Biomaterials, 2008 - Elsevier
A kinetic study was performed to determine the influence of particle size on the in vivo tissue
distribution of spherical-shaped gold nanoparticles in the rat. Gold nanoparticles were …

Application of plasma spectrometry for the analysis of engineered nanoparticles in suspensions and products

P Krystek, A Ulrich, CC Garcia, S Manohar… - Journal of Analytical …, 2011 - pubs.rsc.org
This article reviews the general characterization of nano-objects, especially engineered
nanoparticles (ENPs) and discusses analytical techniques commonly used for their …

[HTML][HTML] Progress and future of in vitro models to study translocation of nanoparticles

…, S Bellmann, M van der Zande, S Le Gac, P Krystek… - Archives of …, 2015 - Springer
The increasing use of nanoparticles in products likely results in increased exposure of both
workers and consumers. Because of their small size, there are concerns that nanoparticles …

Inhaled nanoparticles accumulate at sites of vascular disease

…, AT Vesey, PHB Fokkens, AJF Boere, P Krystek… - ACS …, 2017 - ACS Publications
The development of engineered nanomaterials is growing exponentially, despite concerns
over their potential similarities to environmental nanoparticles that are associated with …

Presence and risks of nanosilica in food products

S Dekkers, P Krystek, RJB Peters, DPK Lankveld… - …, 2011 - Taylor & Francis
This study uniquely describes all steps of the risk assessment process for the use of one
specific nanomaterial (nanosilica) in food products. The aim was to identify gaps in essential …

[HTML][HTML] Tissue distribution and elimination after oral and intravenous administration of different titanium dioxide nanoparticles in rats

L Geraets, AG Oomen, P Krystek, NR Jacobsen… - Particle and fibre …, 2014 - Springer
Objective The aim of this study was to obtain kinetic data that can be used in human risk
assessment of titanium dioxide nanomaterials. Methods Tissue distribution and blood kinetics of …

[HTML][HTML] Particle size dependent deposition and pulmonary inflammation after short-term inhalation of silver nanoparticles

HM Braakhuis, I Gosens, P Krystek, JAF Boere… - Particle and fibre …, 2014 - Springer
Background Although silver nanoparticles are currently used in more than 400 consumer
products, it is not clear to what extent they induce adverse effects after inhalation during …

Blood clearance and tissue distribution of PEGylated and non-PEGylated gold nanorods after intravenous administration in rats

DPK Lankveld, RG Rayavarapu, P Krystek… - …, 2011 - Future Medicine
Aims: To develop and determine the safety of gold nanorods, whose aspect ratios can be
tuned to obtain plasmon peaks between 650 and 850 nm, as contrast enhancing agents for …

Identification of the appropriate dose metric for pulmonary inflammation of silver nanoparticles in an inhalation toxicity study

…, LJJ De La Fonteyne, AG Oomen, P Krystek… - …, 2016 - Taylor & Francis
A number of studies have shown that induction of pulmonary toxicity by nanoparticles of the
same chemical composition depends on particle size, which is likely in part due to …

[HTML][HTML] The biological effects of subacute inhalation of diesel exhaust following addition of cerium oxide nanoparticles in atherosclerosis-prone mice

…, AJF Boere, SG McLean, R Duffin, P Krystek… - Environmental …, 2012 - Elsevier
BACKGROUND: Cerium oxide (CeO 2 ) nanoparticles improve the burning efficiency of fuel,
however, little is known about health impacts of altered emissions from the vehicles. …