Biologics (mepolizumab and omalizumab) induced remission in severe asthma patients

…, PN Reynolds, J Rimmer, P Sivakumaran… - Allergy, 2024 - Wiley Online Library
Background Asthma remission has emerged as a potential treatment goal. This study
evaluated the effectiveness of two biologics (mepolizumab/omalizumab) in achieving asthma …

Comorbidities modify the phenotype but not the treatment effectiveness to mepolizumab in severe eosinophilic asthma

…, HK Reddel, PN Reynolds, P Sivakumaran… - The Journal of Allergy …, 2023 - Elsevier
Background Comorbidities in severe asthma are common and contribute to disease burden.
The severe asthma phenotype and treatment response can be impacted by comorbid …

Mepolizumab and oral corticosteroid stewardship: data from the Australian Mepolizumab Registry

…, HK Reddel, J Rimmer, P Sivakumaran… - The Journal of Allergy …, 2021 - Elsevier
Background Oral corticosteroids (OCS) carry serious health risks. Innovative treatment options
are required to reduce excessive exposure and promote OCS stewardship. Objectives …

Laparoscopic retroperitoneal left adrenalectomy in a patient with Cushing's syndrome

…, SH Purchas, P Sivakumaran… - Australian and New …, 1994 - Wiley Online Library
A technique for the extraperitoneal removal of the adrenal gland using laparoscopic
instrumentation and insufflation is described. A case of Cushing's syndrome in a 42 year old female …

Pleural effusion in patients with pulmonary embolism

…, J Donald, CA Wong, YCG Lee, P Sivakumaran - …, 2008 - Wiley Online Library
Background and objective: It has been suggested that pulmonary embolism (PE) is an under‐recognized
cause of pleural effusion. This study aimed to (i) establish the incidence and …

[HTML][HTML] Emergency department management of acute exacerbations of chronic obstructive pulmonary disease and factors associated with hospitalization

B Khialani, P Sivakumaran, G Keijzers… - Journal of Research in …, 2014 - ncbi.nlm.nih.gov
Background: Currently there is a paucity of information about biomarkers that can predict
hospitalization for acute exacerbations of chronic obstructive pulmonary disease (AECOPD) …

[HTML][HTML] Differences in care between general medicine and respiratory specialists in the management of patients hospitalized for acute exacerbations of chronic …

K Wijayaratne, J Wilson, P Sivakumaran… - Annals of thoracic …, 2013 - journals.lww.com
AIMS: The aims of this study were to firstly examine the differences in AECOPD management
of GMP and RS and secondly compare their care to national COPD guidelines. METHODS: …

[HTML][HTML] Non-typeable Haemophilus Influenzae detection in the lower airways of patients with lung cancer and chronic obstructive pulmonary disease

KB Sriram, AJ Cox, P Sivakumaran, M Singh… - Multidisciplinary …, 2018 - Springer
Background Chronic airway inflammation and hypersensitivity to bacterial infection may
contribute to lung cancer pathogenesis. Previous studies have demonstrated that nontypeable …

Asbestos-induced and Smoking-related Disease: Apportioning Pulmonary Function Deficit by Using Thin-Section CT1

SJ Copley, YCG Lee, DM Hansell, P Sivakumaran… - Radiology, 2007 - pubs.rsna.org
Purpose: To retrospectively correlate the extent of individual diseases seen at thin-section
computed tomography (CT) with pulmonary function in an initial group of patients with …

The training, experience, and confidence of junior doctors in performing pleural procedures

…, H Kenealy, C Hood, P Sivakumaran… - Clinical …, 2009 - search.proquest.com
… Conroy A Wong, Olivia Lee, Yvonne Kennedy, Helen Kenealy, Christopher Hood,
Pathmanathan Sivakumaran, YC Gary Lee … Author information: Conroy A Wong, Consultant …