Impact of obstructive sleep apnea on gestational diabetes mellitus

…, MPG Carrero, CP Martínez, JPC Marín… - Archivos de …, 2022 - Elsevier
Introduction Obstructive sleep apnea (OSA) increases the risk of type 2 diabetes, and
hyperinsulinemia. Pregnancy increases the risk of OSA; however, the relationship between OSA …

[HTML][HTML] Influence of obstructive sleep apnea on systemic inflammation in pregnancy

…, C Pía Martínez, JP Cubero Marín… - Frontiers in …, 2021 - frontiersin.org
Background: Obstructive sleep apnea (OSA) is prevalent in pregnancy and it is associated
with adverse pregnancy-related outcomes such as gestational diabetes, preeclampsia, and …

[HTML][HTML] Stability of circulating exosomal miRNAs in healthy subjects

…, A Gil, P Cubero, M Forner, A Khalyfa, JM Marin - Scientific reports, 2018 - nature.com
Exosomes are nano-vesicles present in the circulation that are involved in cell-to-cell
communication and regulation of different biological processes. MicroRNAs (miRNAs) are part of …

Upper airway and systemic inflammation in obstructive sleep apnoea

…, M Forner, P Vicente, P Cubero… - European respiratory …, 2016 - Eur Respiratory Soc
Obstructive sleep apnoea (OSA) is associated with pharyngeal inflammation, but the
coexistence of systemic inflammation is controversial. This study investigated whether local and …

Long term changes of C-rective protein (CRP) in obstructive sleep apnoea (OSA) with or without treatment

…, DP Alonso, ALS Robles, VG Gomez, PC Marin… - 2016 - Eur Respiratory Soc
INTRODUCTION: Obesity is associated with systemic inflammation, but its relationship with
OSA is controversial. CRP is a predictor of cardiovascular events, that are also is increased …

Inflammasome activation mediated by oxidised low-density lipoprotein in patients with sleep apnoea and early subclinical atherosclerosis

…, E Alfaro, P Cubero, AV Gil, JM Marin… - European …, 2023 - Eur Respiratory Soc
Background Atherosclerosis is a common comorbidity of obstructive sleep apnoea (OSA)
patients, caused by the interaction of dyslipidaemia and systemic inflammation. The OSA pro-…

Inflammation biomarkers in OSA, chronic obstructive pulmonary disease, and chronic obstructive pulmonary disease/OSA overlap syndrome

…, D Sanz-Rubio, M Marin-Oto, P Cubero… - Journal of Clinical …, 2023 - jcsm.aasm.org
Study Objectives: The coexistence of obstructive sleep apnea (OSA) and chronic obstructive
pulmonary disease (COPD) in a single individual, also known as overlap syndrome (OVS), …

[HTML][HTML] SMAD4 Expression in Monocytes as a Potential Biomarker for Atherosclerosis Risk in Patients with Obstructive Sleep Apnea

…, I Cano-Pumarega, P Cubero, M Marin-Oto… - International Journal of …, 2023 - mdpi.com
Obstructive sleep apnea (OSA) patients are at special risk of suffering atherosclerosis, leading
to major cardiovascular diseases. Notably, the transforming growth factor (TGF-β) plays a …

[HTML][HTML] Symptomatic smokers without COPD have physiological changes heralding the development of COPD

…, D Biondini, P Cubero, M Marin-Oto… - ERJ Open …, 2022 - Eur Respiratory Soc
Background COPD is a major health problem, mainly due to cigarette smoking. Most studies
in COPD are dedicated to fully developed COPD in older subjects, even though …

[HTML][HTML] Low-blood lymphocyte number and lymphocyte decline as key factors in COPD outcomes: a longitudinal cohort study

…, B Buldini, SJ Carizzo, P Cubero, M Marin-Oto… - Respiration, 2021 - karger.com
Background: Smokers with and without chronic obstructive pulmonary disease (COPD) are
at risk of severe outcomes like exacerbations, cancer, respiratory failure, and decreased …