Introduction: Adenocarcinoma is the most common histologic type of lung cancer. To
address advances in oncology, molecular biology, pathology, radiology, and surgery of lung …

Cardiac toxicity is one of the most concerning side effects of anti-cancer therapy. The gain in
life expectancy obtained with anti-cancer therapy can be compromised by increased …

Lung cancer is the leading cause of cancer death worldwide. Cancer metastasis and resistance
to treatment (including radiotherapy, chemotherapy and targeted therapy) are two major …

We investigated whether microRNA expression profiles can predict clinical outcome of
NSCLC patients. Using real-time RT-PCR, we obtained microRNA expressions in 112 NSCLC …

… of H820 and PC-9 … PC-9 cells, a lung cancer line that harbors an exon 19 deletion (E746-A750)
of EGFR but no T790M mutation and no MET amplification (Table 2). Extracts from PC-9 …

Background Current staging methods are inadequate for predicting the outcome of treatment
of non–small-cell lung cancer (NSCLC). We developed a five-gene signature that is closely …

Western blotting is an important technique used in cell and molecular biology. By using a
western blot, researchers are able to identify specific proteins from a complex mixture of …

Flt-4, a VEGF receptor, is activated by its specific ligand, VEGF-C. The resultant signaling
pathway promotes angiogenesis and/or lymphangiogenesis. This report provides evidence …

Introduction: PIONEER (NCT01185314) was a prospective, multinational, epidemiological
study of epidermal growth factor receptor (EGFR) mutations in patients from Asia with newly …

A two-dimensional linear theory of motions of heterogeneous plates is deduced from the
three-dimensional theory of elasticity. Transverse shear deformations and rotatory inertia are …