User profiles for P. van Mourik

Pieter van Mourik

retired researcher Delft University of Technology, Faculty of Applied Sciences
Verified email at freeler.nl
Cited by 536

Tissue distribution and biochemical and functional properties of Tp55 (CD27), a novel T cell differentiation antigen.

…, J Borst, TM Vroom, H Klein, P Van Mourik… - … (Baltimore, Md.: 1950 …, 1987 - journals.aai.org
Two monoclonal antibodies (CLB-CD 27/1 and CLB-CD 27/2) were raised against a novel
determinant on human T lymphocytes. One of these antibodies, CLB-CD 27/1 (clone 9F4), …

[PDF][PDF] Rectal organoids enable personalized treatment of cystic fibrosis

G Berkers, P van Mourik, AM Vonk, E Kruisselbrink… - Cell reports, 2019 - cell.com
In vitro drug tests using patient-derived stem cell cultures offer opportunities to individually
select efficacious treatments. Here, we provide a study that demonstrates that in vitro drug …

[PDF][PDF] CRISPR-based adenine editors correct nonsense mutations in a cystic fibrosis organoid biobank

…, R Oka, FM Meijers, E Kruisselbrink, P van Mourik… - Cell stem cell, 2020 - cell.com
Adenine base editing (ABE) enables enzymatic conversion from AT into GC base pairs. ABE
holds promise for clinical application, as it does not depend on the introduction of double-…

[HTML][HTML] Protocol for application, standardization and validation of the forskolin-induced swelling assay in cystic fibrosis human colon organoids

AM Vonk, P van Mourik, AS Ramalho, IAL Silva… - STAR protocols, 2020 - Elsevier
This protocol describes the isolation, handling, culture of, and experiments with human
colon stem cell organoids in the context of cystic fibrosis (CF). In human colon organoids, the …

[HTML][HTML] Standards of care for CFTR variant-specific therapy (including modulators) for people with cystic fibrosis

…, M Shteinberg, I Sinha, C Takawira, P van Mourik… - Journal of Cystic …, 2023 - Elsevier
Cystic fibrosis (CF) has entered the era of variant-specific therapy, tailored to the genetic
variants in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene. CFTR …

Cooling and heating rate dependence of precipitation in an Al—Cu alloy

MJ Starink, P Van Mourik - Materials Science and Engineering: A, 1992 - Elsevier
Differential scanning calorimetry and X-ray diffraction were used to study the cooling and
heating rate dependence of precipitation in an Al-1.66 at.% Cu alloy. After homogenizing, …

Intestinal organoids to model cystic fibrosis

P Van Mourik, JM Beekman… - European Respiratory …, 2019 - Eur Respiratory Soc
Recent advances in adult stem cell biology have resulted in the development of organoid
culture technologies using a variety of tissue sources such as intestine, lung and kidney [1]. …

[HTML][HTML] Potentiator synergy in rectal organoids carrying S1251N, G551D, or F508del CFTR mutations

JF Dekkers, P Van Mourik, AM Vonk… - Journal of Cystic …, 2016 - Elsevier
P values are indicated only for the conditions that were statistically different from the DMSO
P value is indicated only for the condition that is statistically different from the DMSO control …

[HTML][HTML] Forskolin-induced organoid swelling is associated with long-term cystic fibrosis disease progression

D Muilwijk, E De Poel, P Van Mourik… - European …, 2022 - Eur Respiratory Soc
P. van Mourik reports financial compensation (money to institution) from Vertex for
participation in a webinar, outside the submitted work. All other authors have nothing to disclose. …

Precipitation in liquid-quenched Al-Mg alloys; a study using X-ray diffraction line shift and line broadening

P Van Mourik, NM Maaswinkel, TH de Keijser… - Journal of materials …, 1989 - Springer
The precipitation process in liquid-quenched alloys of aluminium with 3.2, 10.5 and 16.7 at%
Mg on ageing at 404, 450 and 492 K was investigated by X-ray diffraction analysis. It was …