occur in patients with idiopathic PPH. 6, 7 Whether these cells are derived from the endothelial
progenitor cells obtained from the mobilization of bone marrow by growth factors such as …

Survival in patients with pulmonary arterial hypertension (PAH) is closely related to right
ventricular (RV) function. Although pulmonary load is an important determinant of RV systolic …

… Hassoun has received research grants from Actelion (Cotherix), the National Institutes of
Health, the National Heart, Lung and Blood Institute, and United Therapeutics. Dr. Mouton has …

Rationale: Right ventricular (RV) function is an important determinant of prognosis in pulmonary
hypertension. However, noninvasive assessment of the RV function is often limited by …

Rationale: Transthoracic Doppler echocardiography is recommended for screening for the
presence of pulmonary hypertension (PH). However, some recent studies have suggested …

… Dr Hassoun has received honoraria for consultations and/or scientific advisory board
activities for Gilead, Pfizer, Novartis, and Merck . Dr Morrell has received a research grant from …

Our prior in vitro studies indicate that sphingosine 1-phosphate (S1P), a phospholipid
angiogenic factor, produces endothelial cell barrier enhancement through ligation of endothelial …

markers such as right atrial pressure, cardiac output, and mean PAP. 8 Importantly, this
procedure has been shown to be safe, with no deaths reported in the National Institutes of Health …

… Hassoun has received research grants from Actelion (Cotherix), the National Institutes of
Health, the National Heart, Lung, and Blood Institute, and United Therapeutics. Dr. Lang has …

… Dr Hassoun has received research funding support from Actelion/CoTherix Inc and is on
the Advisory Board for Novartis. Dr McGoon has received research funding from Gilead and …