Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma
…, J Solway, NL Stephens, PJ Sterk… - European …, 2007 - Eur Respiratory Soc
Excessive airway obstruction is the cause of symptoms and abnormal lung function in asthma.
As airway smooth muscle (ASM) is the effecter controlling airway calibre, it is suspected …
As airway smooth muscle (ASM) is the effecter controlling airway calibre, it is suspected …
Standardized challenge testing with pharmacological, physical and sensitizing stimuli in adults
PJ Sterk, LM Fabbri, PH Quanjer… - European …, 1993 - Eur Respiratory Soc
Asthma and chronic obstructive pulmonary disease (COPD, also called chronic airflow limitation
(CAL)) are the most frequent diagnoses in patients with intrathoracic airways ob truction […
(CAL)) are the most frequent diagnoses in patients with intrathoracic airways ob truction […
Nitric oxide in health and disease of the respiratory system
FLM Ricciardolo, PJ Sterk, B Gaston… - Physiological …, 2004 - journals.physiology.org
During the past decade a plethora of studies have unravelled the multiple roles of nitric oxide
(NO) in airway physiology and pathophysiology. In the respiratory tract, NO is produced by …
(NO) in airway physiology and pathophysiology. In the respiratory tract, NO is produced by …
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response
…, TT Hansel, ST Holgate, PJ Sterk, PJ Barnes - The Lancet, 2000 - thelancet.com
Background Interleukin-5 (IL-5) is essential for the formation of eosinophils, which are thought
to have a major role in the pathogenesis of asthma and other allergic diseases. We aimed …
to have a major role in the pathogenesis of asthma and other allergic diseases. We aimed …
Risk factors of frequent exacerbations in difficult-to-treat asthma
A Ten Brinke, PJ Sterk, AAM Masclee… - European …, 2005 - Eur Respiratory Soc
Recurrent exacerbations are a major cause of morbidity and medical expenditure in patients
with asthma. Various exogenous and endogenous factors are thought to influence the level …
with asthma. Various exogenous and endogenous factors are thought to influence the level …
An electronic nose in the discrimination of patients with asthma and controls
BACKGROUND: Exhaled breath contains thousands of volatile organic compounds (VOCs)
that could serve as biomarkers of lung disease. Electronic noses can distinguish VOC …
that could serve as biomarkers of lung disease. Electronic noses can distinguish VOC …
International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
Severe or therapy-resistant asthma is increasingly recognised as a major unmet need. A
Task Force, supported by the European Respiratory Society and American Thoracic Society, …
Task Force, supported by the European Respiratory Society and American Thoracic Society, …
Guidelines for methacholine and exercise challenge testing-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors …
…, JE Fish, PJ Sterk - American …, 2000 - researchinformation.amsterdamumc …
… Casaburi, AL Coates, PL Enright, JL Hankinson, CG Irvin, NR MacIntyre, RT McKay, JS
Wanger, SD Anderson, DW Cockcroft, JE Fish, PJ Sterk …
Wanger, SD Anderson, DW Cockcroft, JE Fish, PJ Sterk …
An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials …
Background: The assessment of asthma control is pivotal to the evaluation of treatment
response in individuals and in clinical trials. Previously, asthma control, severity, and …
response in individuals and in clinical trials. Previously, asthma control, severity, and …
Clinical control and histopathologic outcome of asthma when using airway hyperresponsiveness as an additional guide to long-term treatment
…, JANP VANDENBROUCKE, PJ STERK… - American journal of …, 1999 - atsjournals.org
According to international guidelines, the level and adjustment of antiinflammatory treatment
for asthma are based solely on symptoms and lung function. We investigated whether a …
for asthma are based solely on symptoms and lung function. We investigated whether a …