In the decade since the last Lancet Seminar on lung cancer there have been advances in
many aspects of the classification, diagnosis, and treatment of non-small-cell lung cancer (…

This article proposes codes for the primary tumor categories of adenocarcinoma in situ (AIS)
and minimally invasive adenocarcinoma (MIA) and a uniform way to measure tumor size in …

Malignant pleural effusions are a common clinical problem in patients with neoplastic disease.
In one post mortem series, malignant effusions were found in 15% of patients who died …

The IASLC Staging and Prognostic Factors Committee has collected a new database of
94,708 cases donated from 35 sources in 16 countries around the globe. This has now been …

Cancers arise owing to mutations in a subset of genes that confer growth advantage. The
availability of the human genome sequence led us to propose that systematic resequencing of …

Introduction The seventh edition of the TNM Classification of Malignant Tumors is due to be
published early in 2009. In preparation for this, the International Association for the Study of …

Objectives: The International Registry of Lung Metastases was established in 1991 to assess
the long-term results of pulmonary metastasectomy. Methods: The Registry has accrued …

The accurate assessment of lymph node involvement is an important part of the management
of lung cancer. Lymph node “maps” have been used to describe the location of nodal …

The protein-kinase family is the most frequently mutated gene family found in human cancer
and faulty kinase enzymes are being investigated as promising targets for the design of …

Introduction Accurate staging of lymph node involvement is a critical aspect of the initial
management of nonmetastatic non-small cell lung cancer (NSCLC). We sought to determine …