The fly Drosophila melanogaster is one of the most intensively studied organisms in biology
and serves as a model system for the investigation of many developmental and cellular …

We report a high-quality draft of the genome sequence of the grey, short-tailed opossum (Monodelphis
domestica). As the first metatherian (‘marsupial’) species to be sequenced, the …

Tumor heterogeneity of high-grade glioma (HGG) is recognized by four clinically relevant
subtypes based on core gene signatures. However, molecular signaling in glioma stem cells (…

STAMP is a newly developed web server that is designed to support the study of DNA-binding
motifs. STAMP may be used to query motifs against databases of known motifs; the …

Rationale: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and usually lethal
fibrotic lung disease characterized by profound changes in epithelial cell phenotype and …

… Gibson reviewed clinical data; PV Benos supervised graphical modelling; W. Chen supervised
RNA-sequencing analysis; C. … Conflict of interest: PV Benos has nothing to disclose. …

… Equation 1 is a simplified version of the one presented in Benos et al.(16) in that it does
not include the relative frequencies of the different binding site types. However, these fre…

Man and Stormo and Bulyk et al. recently presented their results on the study of the DNA
binding affinity of proteins. In both of these studies the main conclusion is that the additivity …

Background MicroRNAs (miRNAs) are short, non-coding RNA regulators of protein coding
genes. miRNAs play a very important role in diverse biological processes and various …

Skin and lung fibrosis in systemic sclerosis (SSc) is driven by myofibroblasts, alpha-smooth
muscle actin expressing cells. The number of myofibroblasts in SSc skin correlates with the …