AIM: To review the currently available literature comparing the FEV 1 /FVC <LLN with a
fixed value of FEV 1 /FVC <0.70 in diagnosing airflow obstruction in subjects aged >40 years. …

BACKGROUND: The role of carotid surgery for the management of restenosis after carotid
endarterectomy (CEA) is challenged by carotid artery stenting (CAS). We reviewed redo CEA …

Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality worldwide 1 .
We performed a genetic association study in 15,256 cases and 47,936 controls, with …

… We examined the association P values for airflow obstruction for these 75 SNPs in the
meta-… Accordingly, we considered a P value of 8.6 × 10 −4 as the criterion for statistically …

… FEV 1 showed a mean increase of 52 mL/y (P = .006) and VC of 95 mL/y (P = .001) in
both … cohort (P = .004), and the methotrexate group had a higher Dlco at baseline (P = .01). …

Background The Global initiative for chronic Obstructive Lung Disease (GOLD) defines
COPD as a fixed post-bronchodilator ratio of forced expiratory volume in 1 second and forced …

… From a total of 11 RA loci, only the well-established risk variant in PTPN22 (rs2476601)
showed a clear association with RA in our cohort ( P = 3.43 × 10 −12 ; OR = 1.70 (95% …

BACKGROUND: The optimal particle size of a beta 2 agonist or anticholinergic aerosol in
patients with severe airflow obstruction is unknown. METHODS: Seven stable patients with a …

… The interaction between Perc15 and smoking status was not significant (p=0.704). The
interaction between Perc15 and pack-years smoked was also not significant (p=0.106), indicating …

Context Smoking is a major risk factor for both cancer and chronic obstructive pulmonary
disease (COPD). Computed tomography (CT)–based lung cancer screening may provide an …