PURPOSE: To evaluate the feasibility, safety, and initial therapeutic effect of radiofrequency
(RF) ablation in the treatment of unresectable malignant lung tumors. MATERIALS AND …

It is well recognized that activation of the coagulation system plays an important role in
bleomycin (BLM)-induced lung injury and fibrosis. The protein C (PC) pathway is an important …

Purpose Although cancer cachexia is mainly characterized by persistent loss of body weight
(BW), usually in response to a malignancy, the pathophysiology of cachexia remains …

Rationale: The long-term effects of using a high-flow nasal cannula for chronic hypercapnic
respiratory failure caused by chronic obstructive pulmonary disease remain unclear. …

Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal disease of unknown etiology;
however, apoptosis of lung alveolar epithelial cells plays a role in disease progression. This …

Objectives To describe the treatment patterns and determine the effectiveness and safety of
nivolumab treatment for non-small cell lung cancer (NSCLC) in real-world setting in Japan. …

Idiopathic pulmonary fibrosis is an incurable disease of unknown etiology. Acute exacerbation
of idiopathic pulmonary fibrosis is associated with high mortality. Excessive apoptosis of …

Asthma is one of the most common diseases and is characterized by airway obstruction, airway
inflammation, and increased airway responsiveness. Glucocorticoids are very effective in …

Background Studies have suggested that chemotherapy after immune checkpoint inhibitors
may confer an improved response for non–small cell lung cancer (NSCLC). However, …

Introduction Alectinib and crizotinib have been approved for the therapy of NSCLC caused
by anaplastic lymphoma kinase gene (ALK) rearrangement. The effect of alectinib or …