User profiles for Olivier Burgy

Olivier Burgy, PhD

University of Burgundy
Verified email at u-bourgogne.fr
Cited by 763

Exosome isolation by ultracentrifugation and precipitation and techniques for downstream analyses

C Coughlan, KD Bruce, O Burgy… - Current Protocols in …, 2020 - Wiley Online Library
Exosomes are 50‐ to 150‐nm‐diameter extracellular vesicles secreted by all mammalian
cells except mature red blood cells and contribute to diverse physiological and pathological …

The WNT signaling pathways in wound healing and fibrosis

O Burgy, M Königshoff - Matrix Biology, 2018 - Elsevier
The WNT signaling pathways are major regulators of organ development. Ample research
over the past few decades revealed that these pathways are critically involved in adult tissue …

Increased extracellular vesicles mediate WNT5A signaling in idiopathic pulmonary fibrosis

A Martin-Medina, M Lehmann, O Burgy… - American journal of …, 2018 - atsjournals.org
Rationale: Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease characterized by lung
epithelial cell injury, increased (myo)fibroblast activation, and extracellular matrix deposition. …

Heat shock proteins in fibrosis and wound healing: good or evil?

PS Bellaye, O Burgy, S Causse, C Garrido… - Pharmacology & …, 2014 - Elsevier
Heat shock proteins (HSPs) are key regulators of cell homeostasis, and their cytoprotective
role has been largely investigated in the last few decades. However, an increasing amount of …

TRIM33 prevents pulmonary fibrosis by impairing TGF-β1 signalling

PM Boutanquoi, O Burgy, G Beltramo… - European …, 2020 - Eur Respiratory Soc
Background Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterised by
myofibroblast proliferation and abnormal extracellular matrix accumulation in the lungs. …

[HTML][HTML] Syndecan-1 promotes lung fibrosis by regulating epithelial reprogramming through extracellular vesicles

…, PW Noble, CM Hogaboam, N Deng, O Burgy… - JCI insight, 2019 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal lung disease. A maladaptive
epithelium due to chronic injury is a prominent feature and contributor to pathogenic cellular …

HSP47: a potential target for fibrotic diseases and implications for therapy

PS Bellaye, O Burgy, P Bonniaud… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction: Chronic fibrotic disorders are challenging clinical problems. The major challenge
is the identification of specific targets expressed selectively in fibrotic tissues. Collagen …

The small heat‐shock protein αB‐crystallin is essential for the nuclear localization of Smad4: impact on pulmonary fibrosis

PS Bellaye, G Wettstein, O Burgy… - The Journal of …, 2014 - Wiley Online Library
Idiopathic pulmonary fibrosis ( IPF ) is a devastating disease characterized by the proliferation
of myofibroblasts and the accumulation of extracellular matrix ( ECM ) in the lungs. TGF‐…

Cell‐specific expression of runt‐related transcription factor 2 contributes to pulmonary fibrosis

C Mümmler, O Burgy, S Hermann, K Mutze… - The FASEB …, 2018 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease with limited therapeutic options and
unknown etiology. IPF is characterized by epithelial cell injury, impaired cellular crosstalk …

[HTML][HTML] Extracellular lipids in the lung and their role in pulmonary fibrosis

O Burgy, S Loriod, G Beltramo, P Bonniaud - Cells, 2022 - mdpi.com
Lipids are major actors and regulators of physiological processes within the lung. Initial
research has described their critical role in tissue homeostasis and in orchestrating cellular …