Background The Global Initiative for Asthma recommends the use of as-needed low-dose
inhaled corticosteroid (ICS)-formoterol as a preferred controller therapy for patients with mild …

Nearly 3.8 million Canadians live with asthma and ∼8% of these patients have severe disease,
suffering from frequent exacerbations and leading to increased healthcare costs [1, 2]. In …

Cytochrome c oxidase (COX) activity reflects the expressed level of respiratory chain
complexes, mtDNA levels, titer and mass of mitochondria. Activity is also indicative of the overall …

Asthma is a chronic inflammatory condition that affects 3.8 million Canadians and nearly 65
000 acute asthma exacerbations occur each year [1–4]. Left untreated, asthma can lead to …

Introduction: As many as 8% of patients with asthma in Canada have severe disease (Asthma
Society of Canada, 2014). Patients with severe, eosinophilic asthma may benefit from a …

Background: Up to 8% of patients with asthma in Canada have severe uncontrolled disease
leading to substantial health care utilization. Anti–IL–5 biologics (eg, mepolizumab, …

… The most recent epidemiological data for Sri Lanka comes from the work of Sriskandarajah et
al. (… Niroshan Siriwardena, which has improved the manuscript, is sincerely acknowledged. …

Background: Adverse childhood experiences are major risk factors for poor mental health
outcomes in adulthood. This study explored the effects of child abuse on mental health of …

The aim of the present study was to adapt and validate the ISPCAN child abuse screening
tool-retrospective version (ICAST-R) in Sri Lanka with a view to investigating the experiences …

Clevudine is a nucleoside analog reverse transcriptase inhibitor that exhibits potent antiviral
activity against hepatitis B virus (HBV) without serious side effects. However, mitochondrial …