Early detection of nerve fiber loss by corneal confocal microscopy and skin biopsy in recently diagnosed type 2 diabetes

D Ziegler, N Papanas, A Zhivov, S Allgeier, K Winter… - Diabetes, 2014 - Am Diabetes Assoc
We sought to determine whether early nerve damage may be detected by corneal confocal
microscopy (CCM), skin biopsy, and neurophysiological tests in 86 recently diagnosed type 2 …

Neuropathy in prediabetes: does the clock start ticking early?

N Papanas, AI Vinik, D Ziegler - Nature Reviews Endocrinology, 2011 - nature.com
Between 25% and 62% of patients with idiopathic peripheral neuropathy are reported to
have prediabetes, and among individuals with prediabetes 11–25% are thought to have …

Epidermal growth factor in the treatment of diabetic foot ulcers: an update

EK Tiaka, N Papanas, AC Manolakis… - … in Vascular Surgery …, 2012 - journals.sagepub.com
Management of diabetic foot ulcers remains a rather challenging task. Epidermal growth
factor (EGF) plays a central role in wound healing. It acts on epithelial cells and fibroblasts …

[HTML][HTML] Complications of diabetes 2016

K Papatheodorou, N Papanas, M Banach… - Journal of diabetes …, 2016 - hindawi.com
The prevalence of diabetes (DM) is constantly increasing worldwide at an alarming rate.
According to the International Diabetes Federation in 2015, an estimated 415 million people …

[HTML][HTML] Risk factors and comorbidities in diabetic neuropathy: an update 2015

N Papanas, D Ziegler - The review of diabetic studies: RDS, 2015 - ncbi.nlm.nih.gov
Distal symmetric sensorimotor polyneuropathy (DSPN) is the most common neurological
manifestation in diabetes. Major risk factors of DSPN include diabetes duration, hyperglycemia, …

Emerging biomarkers, tools, and treatments for diabetic polyneuropathy

GJ Bönhof, C Herder, A Strom, N Papanas… - Endocrine …, 2019 - academic.oup.com
Diabetic neuropathy, with its major clinical sequels, notably neuropathic pain, foot ulcers, and
autonomic dysfunction, is associated with substantial morbidity, increased risk of mortality, …

[HTML][HTML] Complications of diabetes

…, M Banach, M Edmonds, N Papanas… - Journal of diabetes …, 2015 - hindawi.com
Diabetes is justly recognized as an emerging global epidemic, representing one of the leading
causes of morbidity and mortality worldwide. Hyperglycemia, the common characteristic …

Epidemiology of polyneuropathy in diabetes and prediabetes

D Ziegler, N Papanas, AI Vinik, JE Shaw - Handbook of clinical neurology, 2014 - Elsevier
Diabetic distal symmetric sensorimotor polyneuropathy (DSPN) represents a major health
problem, associated with excruciating neuropathic pain, increased morbidity and impaired …

Efficacy of α-lipoic acid in diabetic neuropathy

N Papanas, D Ziegler - Expert Opinion on Pharmacotherapy, 2014 - Taylor & Francis
Introduction: Neuropathy is a serious complication of diabetes. Its management focuses on
glycaemic control, multifactorial cardiovascular risk intervention, pathogenesis-oriented …

The diabetic hand: a forgotten complication?

N Papanas, E Maltezos - Journal of Diabetes and its Complications, 2010 - Elsevier
The manifestations of diabetes in the hand were much discussed in the 1970s and 1980s.
The present review aims to revisit the diabetic hand and to discuss the pathology of the hand …