User profiles for NC Barnes

Neil Barnes

Professor
Verified email at gsk.com
Cited by 15560

Antibiotics for exacerbations of chronic obstructive pulmonary disease

…, J Garcia‐Aymerich, NC Barnes - Cochrane Database …, 2006 - cochranelibrary.com
Background Most patients with an exacerbation of chronic obstructive pulmonary disease (COPD)
are treated with antibiotics. However the value of their use remains uncertain. Some …

[HTML][HTML] Choosing inhaler devices for people with asthma: current knowledge and outstanding research needs

J Haughney, D Price, NC Barnes, JC Virchow… - Respiratory …, 2010 - Elsevier
Recommendations in asthma guidelines presuppose that practitioners have the evidence,
information, knowledge, and tools to select inhaler devices appropriate for individual patients. …

Genistein, daidzein, and their. beta.-glycoside conjugates: antitumor isoflavones in soybean foods from American and Asian diets

…, NC Barnes, KDR Setchell, S Barnes - Journal of agricultural …, 1993 - ACS Publications
Barnes, unpublished data) suggest that hot extraction … Barnes, unpublished data). This
may have been the case for the tofu … G.; Barnes, S. Genistein inhibition of the grown of human …

Chronic obstructive pulmonary disease: a modifiable risk factor for cardiovascular disease?

IS Stone, NC Barnes, SE Petersen - Heart, 2012 - heart.bmj.com
Significant cardiac morbidity and mortality exists in patients with COPD. Shared risk factors
include age, smoking history and exposure to air pollution and passive smoke. Although the …

Inflammation in bronchial biopsies of subjects with chronic bronchitis: inverse relationship of CD8+ T lymphocytes with FEV1.

TC O'Shaughnessy, TW Ansari, NC Barnes… - American journal of …, 1997 - atsjournals.org
In order to determine whether the airway inflammatory cells of chronic obstructive pulmonary
disease (COPD) are different from those seen in asthma, we have studied a subepithelial …

A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma

…, W Busse, TT Hansel, NC Barnes… - American journal of …, 2007 - atsjournals.org
Rationale: Accumulation of eosinophils in the bronchial mucosa of individuals with asthma
is considered to be a central event in the pathogenesis of asthma. In animal models, airway …

Blood eosinophil counts, exacerbations, and response to the addition of inhaled fluticasone furoate to vilanterol in patients with chronic obstructive pulmonary disease …

…, N Locantore, MT Dransfield, NC Barnes… - The lancet Respiratory …, 2015 - thelancet.com
Background The short-term benefits of inhaled corticosteroids for patients with chronic
obstructive pulmonary disease (COPD) are greater in patients with evidence of eosinophilic …

Antiinflammatory effects of salmeterol/fluticasone propionate in chronic obstructive lung disease

NC Barnes, YS Qiu, ID Pavord, D Parker… - American journal of …, 2006 - atsjournals.org
Rationale: No currently available treatment is reported to reduce the exaggerated airway
wall inflammation of chronic obstructive pulmonary disease. Objectives: We tested the …

Blood eosinophils and inhaled corticosteroid/long-acting β-2 agonist efficacy in COPD

…, S Pascoe, PW Jones, JA Wedzicha, NC Barnes - Thorax, 2016 - thorax.bmj.com
Objective We performed a review of studies of fluticasone propionate (FP)/salmeterol (SAL) (combination
inhaled corticosteroid (ICS)/long-acting β2-agonist (LABA)) in patients with …

The effects of inhaled fluticasone on airway inflammation in chronic obstructive pulmonary disease: a double-blind, placebo-controlled biopsy study

…, TW Ansari, PK Jeffery, NC Barnes - American Journal of …, 2002 - atsjournals.org
Inhaled corticosteroids (ICS) are effective in the treatment of asthma and markedly reduce
the numbers of inflammatory cells in bronchial biopsies. However, the effect of ICS on the …