Bortezomib-induced peripheral neurotoxicity: a neurophysiological and pathological study in the rat
…, C Ceresa, P Marmiroli, M Bossi, N Oggioni… - Experimental …, 2007 - Elsevier
… control rats(mean values ± SD, n = 8 in each group until the end of treatment, then n = 4 …
values ± SD, n = 8 in each group until the end of treatment, then n = 4 until the end of follow-up). …
values ± SD, n = 8 in each group until the end of treatment, then n = 4 until the end of follow-up). …
Erythropoietin both protects from and reverses experimental diabetic neuropathy
…, C Savino, G Cavaletti, N Oggioni… - Proceedings of the …, 2004 - National Acad Sciences
Erythropoietin (EPO) possesses generalized neuroprotective and neurotrophic actions. We
tested the efficacy of recombinant human EPO (rhEPO) in preventing and reversing nerve …
tested the efficacy of recombinant human EPO (rhEPO) in preventing and reversing nerve …
Distribution of paclitaxel within the nervous system of the rat after repeated intravenous administration.
G Cavaletti, E Cavalletti, N Oggioni, C Sottani… - …, 2000 - europepmc.org
The distribution of paclitaxel (Taxol) within the central and peripheral nervous system after
repeated administration of this antineoplastic agent is still largely unknown. In this study we …
repeated administration of this antineoplastic agent is still largely unknown. In this study we …
Effect on the peripheral nervous system of the short-term intravenous administration of paclitaxel in the rat.
G Cavaletti, E Cavalletti, P Montaguti, N Oggioni… - …, 1997 - europepmc.org
The effectiveness of paclitaxel (Taxol) in the treatment of different tumors is well-known but,
on the other hand, there is little information regarding its neurotoxicity and the mechanism (s) …
on the other hand, there is little information regarding its neurotoxicity and the mechanism (s) …
Neurophysiological and neuropathological characterization of new murine models of chemotherapy-induced chronic peripheral neuropathies
VA Carozzi, A Canta, N Oggioni, B Sala… - Experimental …, 2010 - Elsevier
Cisplatin, paclitaxel and bortezomib belong to some of the most effective families of
chemotherapy drugs for solid and haematological cancers. Epothilones represent a new family of …
chemotherapy drugs for solid and haematological cancers. Epothilones represent a new family of …
Bortezomib-induced painful neuropathy in rats: a behavioral, neurophysiological and pathological study in rats
…, A Canta, VA Carozzi, A Chiorazzi, N Oggioni… - European Journal of …, 2010 - Elsevier
… rats treated with the highest dose (0.20 mg/kg) show only a partial recovery (mean values
± SD, n = 12 in each group during the treatment period, n = 6 during the follow-up period). …
± SD, n = 12 in each group during the treatment period, n = 6 during the follow-up period). …
Protective effect of erythropoietin and its carbamylated derivative in experimental Cisplatin peripheral neurotoxicity
…, G Nicolini, V Rodriguez-Menendez, N Oggioni… - Clinical cancer …, 2006 - AACR
Purpose: Antineoplastic drugs, such as cisplatin (CDDP), are severely neurotoxic, causing
disabling peripheral neuropathies with clinical signs known as chemotherapy-induced …
disabling peripheral neuropathies with clinical signs known as chemotherapy-induced …
[HTML][HTML] Bortezomib-induced painful peripheral neuropathy: an electrophysiological, behavioral, morphological and mechanistic study in the mouse
…, G Fazio, A Chiorazzi, C Meregalli, N Oggioni… - PloS one, 2013 - journals.plos.org
… In experiment 2 (time-course is summarized in Figure 1), mice were randomly assigned
to 3 groups (n=8/group) and all housed under the conditions previously described for …
to 3 groups (n=8/group) and all housed under the conditions previously described for …
Lowering plasma 1-deoxysphingolipids improves neuropathy in diabetic rats
…, R Lombardi, A Chiorazzi, C Meregalli, N Oggioni… - Diabetes, 2015 - Am Diabetes Assoc
… usually conjugated to a variety of N-linked fatty acids and different head groups. Because
we were primarily interested in the sphingoid base profile, the N-acyls and head groups were …
we were primarily interested in the sphingoid base profile, the N-acyls and head groups were …
Expression and distribution of 'high affinity'glutamate transporters GLT1, GLAST, EAAC1 and of GCPII in the rat peripheral nervous system
VA Carozzi, A Canta, N Oggioni, C Ceresa… - Journal of …, 2008 - Wiley Online Library
l‐Glutamate is one of the major excitatory neurotransmitters in the mammalian central nervous
system, but recently it has been shown to have a role also in the transduction of sensory …
system, but recently it has been shown to have a role also in the transduction of sensory …