Human airway mucin glycosylation: a combinatory of carbohydrate determinants which vary in cystic fibrosis

…, A Scharfman, M Davril, JM Lo-Guidice, N Houdret… - Glycoconjugate …, 2001 - Springer
Human airway mucins represent a very broad family of polydisperse high molecular mass
glycoproteins, which are part of the airway innate immunity. Apomucins, which correspond to …

Metformin-associated lactic acidosis: a prognostic and therapeutic study

A Seidowsky, S Nseir, N Houdret… - Critical care medicine, 2009 - journals.lww.com
… The cumulative duration of HD in this latter group was significantly different between survivors
(n = 13) and nonsurvivors (n = 14) with a mean value of 17.4 vs. 10.4 hours, respectively (…

The carbohydrate diversity of human respiratory mucins: a protection of the underlying mucosa

G Lamblin, M Lhermitte, A Klein, N Houdret… - Am Rev Respir …, 1991 - atsjournals.org
N-acetylglucosamine residue is linked ~1-3 to N-acetylgalactosamine. Cores 2 and 4
result from addition of N-acetylglucosamine linked ~1-6 to the N-… substituted by N-acetylneuraminic …

The complexity of mucins

P Roussel, G Lamblin, M Lhermitte, N Houdret… - Biochimie, 1988 - Elsevier
N-acetylglucosamine (linked B 1-6) to the N-acetylgalactosamine residue, and the
glycosyltransferase responsible for this synthesis has been detected in several tissue [82, 83]; core 5 …

High-performance liquid chromatographic method to screen and quantitate seven selective serotonin reuptake inhibitors in human serum

G Tournel, N Houdret, V Hedouin, M Deveaux… - … of Chromatography B …, 2001 - Elsevier
A high-performance liquid chromatographic screening method (HPLC) is described for the
determination of seven selective serotonin reuptake inhibitors (SSRIs) (fluvoxamine, …

Pseudomonas aeruginosa recognizes carbohydrate chains containing type 1 (Gal beta 1-3GlcNAc) or type 2 (Gal beta 1-4GlcNAc) disaccharide units

…, C Carnoy, S Fievre, JC Michalski, N Houdret… - Infection and …, 1991 - Am Soc Microbiol
The adhesion of Pseudomonas aeruginosa to type 1 (Gal beta 1-3GlcNAc) and type 2 (Gal
beta 1-4GlcNAc) disaccharide determinants was studied in a microtiter adhesion assay and a …

Characterisation of novel defective thiopurine S-methyltransferase allelic variants

…, D Allorge, D Chevalier, N Houdret… - Biochemical …, 2008 - Elsevier
Human thiopurine S-methyltransferase (TPMT, EC 2.1.1.67) is a key enzyme in the
detoxification of thiopurine drugs widely used in the treatment of various diseases, such as …

Altered Carbohydrate Composition of Salivary Mucins from Patients with Cystic Fibrosos and the Adhesion of Pseudomonas aeruginosa

…, A Scharfman, JM Lo-Guidice, N Houdret… - American journal of …, 1993 - atsjournals.org
We compared the chemical composition of salivary mucin glycopeptides from cystic fibrosis (CF)
and from non-CF subjects and the adhesion of Pseudomonas aeruginosa to these …

Evidence for a functional genetic polymorphism of the human thiosulfate sulfurtransferase (Rhodanese), a cyanide and H2S detoxification enzyme

…, E Rat, C Cauffiez, D Chevalier, N Houdret… - Toxicology, 2006 - Elsevier
Rhodanese or thiosulfate sulfurtransferase (TST) is a mitochondrial matrix enzyme that plays
roles in cyanide detoxification, the formation of iron–sulfur proteins and the modification of …

Complex structure of human bronchial mucus glycoprotein

…, ALE TREUT, C Galabert, N Houdret… - European journal of …, 1984 - Wiley Online Library
Human bronchial mucus glycoproteins or mucins were isolated from the sputum of two patients
by a method avoiding reducing agents and involving water extraction and gel filtration on …