Recent advances in cancer therapy encounter a bottleneck. Relapsing/recurrent disease
almost always developed eventually with resistance to the initially effective drugs. Tumor …

Communication between cancer cells and their microenvironment plays an important role in
cancer development, but the precise mechanisms by which cancer-associated fibroblasts (…

Background Clinicians are increasingly recognizing severe asthma patients in whom biologics
and other add-on therapies lead to dramatic improvement. Currently, there is no agreed-…

The World Health Organization announced the coronavirus disease 2019 (COVID‐19)
outbreak a pandemic on 12 March 2020. Although being in proximity to China, the original …

Objectives Gefitinib is currently used as a first-line therapy in patients of advanced non-small
cell lung cancer (NSCLC) with susceptible epidermal growth factor receptor (EGFR) …

The ability to detect cancer at an early stage in patients who would benefit from effective therapy
is a key factor in increasing survivability. This work proposes an evolutionary supervised …

Previous in vitro and in vivo studies have demonstrated the potential of using cysteinyl
leukotriene receptor antagonists (LTRAs) for chemoprevention, but this has not been investigated …

Developing novel chemo-prevention techniques and advancing treatment are key elements
to beating lung cancer, the most common cause of cancer mortality worldwide. Our previous …

Bladder urothelial carcinoma (BLC) is one of the most common cancers in men, and its
heterogeneity challenges the treatment to cure this disease. Recently, microRNAs (miRNAs) …

Objectives Higher risk of lung cancer has been noted in patients with type 2 diabetes
mellitus (DM). Some observational studies have shown a reduced risk of lung cancer in DM …