Rationale: Anaerobic bacteria are present in large numbers in the airways of people with
cystic fibrosis (PWCF). In the gut, anaerobes produce short-chain fatty acids (SCFAs) that …

The global population is aging with significant gains in life expectancy particularly in the
developed world. Consequently, greater focus on understanding the processes that underlie …

Anaerobic and aerobic bacteria were quantitated in respiratory samples across three cystic
fibrosis (CF) centres using extended culture methods. Subjects aged 1–69 years who were …

Background Chitinases have recently gained attention in the field of pulmonary diseases,
particularly in asthma and chronic obstructive pulmonary disease, but their potential role in …

Background : Cystic fibrosis (CF) is the indication for transplantation in approximately 15%
of recipients worldwide, and Cystic Fibrosis Lung Transplant Recipients (CFLTRs) have …

Individuals with cystic fibrosis (CF) present with severe airway destruction and extensive
bronchiectasis. It has been assumed that these structural airway changes have occurred …

BACKGROUND: The focus of this study was to characterize a novel biomarker for cystic
fibrosis (CF) that could reflect exacerbations of the disease and could be useful for therapeutic …

Rectal neuroendocrine tumours represent a rare colorectal tumour with a 10 fold increased
prevalence due to incidental detection in the era of colorectal screening. Patient outcomes …

Voriconazole is a broad-spectrum triazole antifungal used to treat invasive fungal infections.
It is commonly used prophylactically in immunocompromized patient cohorts, including …

A 65-year-old man was referred to the respiratory clinic with recurrent chest infections on a
background of stage 3 chronic obstructive pulmonary disease. On examination, there was …