Rapid progress has been made in the development of new diagnostic assays for tuberculosis
in recent years. New technologies have been developed and assessed, and are now …

About 1·3 million people died of tuberculosis in 2012, despite availability of effective drug
treatment. Barriers to improvements in outcomes include long treatment duration (resulting in …

Recent data for the global burden of disease reflect major demographic and lifestyle
changes, leading to a rise in non-communicable diseases. Most countries with high levels of …

Coronavirus disease 2019 (COVID-19) is an acute infection of the respiratory tract that emerged
in late 2019 1 , 2 . Initial outbreaks in China involved 13.8% of cases with severe courses…

2019-nCoV Transmission from Asymptomatic Patient In this report, investigators in Germany
detected the spread of the novel coronavirus (2019-nCoV) from a person who had recently …

Background The Xpert MTB/RIF test for tuberculosis is being rolled out in many countries, but
evidence is lacking regarding its implementation outside laboratories, ability to inform same…

The characteristics of loop-mediated isothermal amplification (LAMP) make it a promising
platform for the molecular detection of tuberculosis (TB) in developing countries. Here, we …

Rationale: Xpert MTB/RIF is a novel automated molecular diagnostic recently endorsed by
the World Health Organization. However, performance-related data from high HIV prevalence …

Background Tuberculosis is the world's leading infectious disease killer. We aimed to
identify shorter, safer drug regimens for the treatment of tuberculosis. Methods We did a …

Generalist and specialist species differ in the breadth of their ecological niches. Little is known
about the niche width of obligate human pathogens. Here we analyzed a global collection …