Major advances in our understanding of the universe have historically arisen from dramatic
improvements in our ability to “see.” We have developed progressively larger telescopes …

Leaders should be a key source of ethical guidance for employees. Yet, little empirical research
focuses on an ethical dimension of leadership. We propose social learning theory as a …

SPOTLIGHT Critical review thesis. Like SREBP-1a, SREBP-2 has a long transcriptional
activation domain, but it preferentially activates cholesterol synthesis (1). SREBP-1a and SREBP-…

The mevalonate pathway produces isoprenoids that are vital for diverse cellular functions,
ranging from cholesterol synthesis to growth control. Several mechanisms for feedback …

IN 1901, AFTER STUDYING A PATIENT WITH BLACK URINE, A physician named Archibald
Garrod suggested thata single mutant gene can produce a discrete block in a biochemical …

Animal cells must regulate their biosynthetic pathways so as to produce the required amounts
of end-products without risking overproduction. Such control is particularly important in …

Our literature review focuses on the emerging construct of ethical leadership and compares
this construct with related concepts that share a common concern for a moral dimension of …

Background Remdesivir improves clinical outcomes in patients hospitalized with moderate-to-severe
coronavirus disease 2019 (Covid-19). Whether the use of remdesivir in …

Resident mouse peritoneal macrophages were shown to take up and degrade acetylated
125 I-labeled low density lipoprotein ( 125 I-acetyl-LDL) in vitro at rates that were 20-fold …

Background and Purpose— The purpose of these guidelines is to provide an up-to-date
comprehensive set of recommendations in a single document for clinicians caring for adult …