It is not known at what age lung function impairment may arise in children with cystic fibrosis
(CF). We assessed lung function shortly after birth in infants with CF diagnosed by newborn …

Background Cystic fibrosis per se can sometimes lead to hyponatremia, hypokalemia,
hypochloremia or hyperbicarbonatemia. This tendency was first documented 60 years ago and …

Spontaneous pneumomediastinum is an uncommon benign condition that is occasionally
associated with air within the spinal canal. We describe a further case in a 14-year-old girl and …

Animal models suggest that reduced nitric oxide (NO) synthase activity results in lower
values of exhaled NO (eNO) present at birth in those individuals who are going to develop …

Primary Ciliary Dyskinesia (PCD) is a rare hereditary, multi-organ disease caused by defects
in ciliary structure and function. It results in a wide range of clinical manifestations, most …

Chronic lung disease leads to morbidity and mortality in patients with cystic fibrosis (CF) [1].
Computed tomography imaging of the lung has revealed that lung disease starts early in life …

A 3-year-old boy was found to have a mixed tubulopathy with hypokalemia (1.9 mmol/l),
alkalosis (blood pH 7.51, plasma carbon dioxide pressure 46 mm Hg, plasma bicarbonate 35.7 …

Lower respiratory tract infections (LRTIs) are a driving factor for lung function decline in children
with cystic fibrosis (CF). The respiratory microbiota is closely related to the pathogenesis …

A 12-week-old boy was admitted with rapidly increasing inspiratory stridor, hoarseness,
feeding difficulties, and vomiting. Signs of respiratory distress with tachypnea, nasal flaring, …

Abstract Adrenocortical tumors are rare in children and present with variable signs depending
on the type of hormone excess. We herein describe the unusual presentation of a child …