Eosinophils are pleiotropic multifunctional leukocytes involved in initiation and propagation
of inflammatory responses and thus have important roles in the pathogenesis of …

Background A close relation between asthma and allergic rhinitis has been reported by several
epidemiological and clinical studies. However, the nature of this relation remains unclear…

Many "complex" human diseases, which involve multiple genetic and environmental determinants,
have increased in incidence during the past 2 decades. During the same time period, …

Allergen‐induced secretion of Th2‐type cytokines and IgE production have recently been
reported to be increased in mice treated with 1,25(OH) 2 D, the active form of vitamin D. Our …

Background: Early life development may influence subsequent respiratory morbidity. The
impact of factors determined in childhood on adult lung function, decline in lung function and …

OBJECTIVES--To examine whether road traffic in a big city has a direct effect on pulmonary
function and respiratory symptoms in children. DESIGN--Cross sectional study. SETTING--Of …

Pulmonary function measures reflect respiratory health and are used in the diagnosis of
chronic obstructive pulmonary disease. We tested genome-wide association with forced …

Rationale: Few studies have investigated the factors associated with the early inception of
chronic obstructive pulmonary disease (COPD). Objectives: We investigated COPD risk …

Atopic dermatitis (AD) is a commonly occurring chronic skin disease with high heritability.
Apart from filaggrin (FLG), the genes influencing atopic dermatitis are largely unknown. We …

Rationale: The few prospective studies aimed at assessing the incidence of chronic obstructive
pulmonary disease (COPD) in relation to the presence of chronic cough/phlegm have …