Macrophages are considered to contribute to chronic inflammatory diseases such as rheumatoid
arthritis 1 . However, both the exact origin and the role of macrophages in inflammatory …

Monomeric serum immunoglobulin A (IgA) can contribute to the development of various
autoimmune diseases, but the regulation of serum IgA effector functions is not well defined. Here…

Human tear fluid is a complex mixture containing over 500 solute proteins, lipids, electrolytes,
mucins, metabolites, hormones and desquamated epithelial cells as well as foreign …

Purpose.: To determine whether dexamethasone (DEX)-induced ocular hypertension (OHT)
in mice mimics the hallmarks of steroid-induced glaucoma (SIG) in humans, including …

Purpose.: To determine the connections between the ciliary muscle (CM), trabecular meshwork
(TM), and Schlemm's canal (SC) and their innervations that allows CM contraction (by …

Gelsolin (GSN), one of the most abundant actin-binding proteins, is involved in cell motility,
shape and metabolism. As a member of the GSN superfamily, GSN is a highly structured …

The regional mechanical properties of brain tissue are not only key in the context of brain
injury and its vulnerability towards mechanical loads, but also affect the behavior and …

Objective Trefoil factor 3 (TFF3, also known as intestinal trefoil factor) is a member of a family
of protease‐resistant peptides containing a highly conserved motif with 6 cysteine residues. …

The purpose of the present studies was to investigate the impact of chronic inflammation of
the lacrimal gland, as occurs in Sjögren’s syndrome, on the morphology and function of …

Sex hormones and insulin have been implicated in articular cartilage metabolism. To
supplement previous findings on the regulation of matrix synthesis with 17β-estradiol and insulin …