Background Major issues in the implementation of screening for lung cancer by means of
low-dose computed tomography (CT) are the definition of a positive result and the …

Background The National Lung Screening Trial (NLST) used risk factors for lung cancer (eg,
≥30 pack-years of smoking and <15 years since quitting) as selection criteria for lung-…

Importance Screening for lung cancer has the potential to reduce mortality, but in addition to
detecting aggressive tumors, screening will also detect indolent tumors that otherwise may …

Background: The optimum screening policy for lung cancer is unknown. Objective: To identify
efficient computed tomography (CT) screening scenarios in which relatively more lung …

Background Selection of candidates for lung cancer screening based on individual risk has
been proposed as an alternative to criteria based on age and cumulative smoking exposure (…

Background Lung cancer is a major health problem. CT lung screening can reduce lung cancer
mortality through early diagnosis by at least 20%. Screening high-risk individuals is most …

Purpose To determine the prevalence of interstitial lung abnormalities (ILAs) at initial computed
tomography (CT) examination and the rate of progression of ILAs on 2-year follow-up CT …

Background Lung cancer screening programs may provide opportunities to reduce smoking
rates among participants. This study evaluates the impact of lung cancer screening results …

Background Results from retrospective studies indicate that selecting individuals for low-dose
CT lung cancer screening on the basis of a highly predictive risk model is superior to using …

It is essential to quantify the impacts of the COVID-19 pandemic on cancer screening, including
for vulnerable sub-populations, to inform the development of evidence-based, targeted …