Background Combined pulmonary fibrosis and emphysema (CPFE) is increasingly recognized,
but its prevalence and prognosis remain unclear. We sought to determine the prevalence…

Background and objective: The clinical associations and prognostic value of cough in IPF
have not been adequately described. The objective of this study was to describe the …

Sarcoidosis is a granulomatous diseases affecting the lungs. Anti-neutrophil cytoplasmic
antibody (ANCA)-associated vasculitis (AAV) is a histologically granulomatous B-mediated …

(1) Background: Sarcoidosis is a chronic multisystem disorder of unknown aetiology, driven
by a T-cell mechanism allowing T-cell attachment and transmigration through the …

Background Sarcoidosis features non-necrotizing granulomas consisting mainly of activated
CD4-lymphocytes. T-cell activation is regulated by immune checkpoint (IC) molecules. The …

Sarcoidosis is a multisystemic idiopathic inflammatory disorder characterized non-caseating
granulomas mainly in lungs and lymph nodes (LLN). T cells, especially CD4 +, play an …

Sarcoidosis is a systemic granulomatous and idiopathic disease mainly affects lungs and
thoracic lymph nodes. No specific markers have been identified although a potential role of …

Sarcoidosis is a multisystemic granulomatous disease of unknown origin, that is generally
presumed to be a T-helper and macrophage-driven disease. Follicular helper CD4+ T (Tfh) …

Results: Seventeen of 193 patients with IPF (8.8%) satisfied criteria for CPFE. Patients with
CPFE had lower fibrosis score (mean difference 4.5%, p= 0.046) and higher FVC (mean …

Patients suffering from severe hypoxemia requiring high flow oxygen administration are
very difficult to treat at home and have a poor quality of life. Transtracheal oxygen therapy (TTO) …