[HTML][HTML] Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an …
Background The safety, effectiveness, and cost-effectiveness of molnupiravir, an oral
antiviral medication for SARS-CoV-2, has not been established in vaccinated patients in the …
antiviral medication for SARS-CoV-2, has not been established in vaccinated patients in the …
Effect of antihypertensive medication reduction vs usual care on short-term blood pressure control in patients with hypertension aged 80 years and older: the …
JP Sheppard, J Burt, M Lown, E Temple, R Lowe… - Jama, 2020 - jamanetwork.com
Importance Deprescribing of antihypertensive medications is recommended for some older
patients with polypharmacy and multimorbidity when the benefits of continued treatment may …
patients with polypharmacy and multimorbidity when the benefits of continued treatment may …
Managing chronic cough as a symptom in children and management algorithms: CHEST guideline and expert panel report
…, KA Keogh, K Lai, AP Lane, C Lilly, K Lim, M Lown… - Chest, 2020 - Elsevier
Background Cough is one of the most common presenting symptoms to general practitioners.
The objective of this article is to collate the pediatric components of the CHEST chronic …
The objective of this article is to collate the pediatric components of the CHEST chronic …
Antibiotic prescription strategies and adverse outcome for uncomplicated lower respiratory tract infections: prospective cough complication cohort (3C) study
…, MJ Thompson, K Knox, A van den Bruel, M Lown… - bmj, 2017 - bmj.com
Objective To assess the impact on adverse outcomes of different antibiotic prescribing
strategies for lower respiratory tract infections in people aged 16 years or more. Design …
strategies for lower respiratory tract infections in people aged 16 years or more. Design …
[HTML][HTML] Predictors of pneumonia in lower respiratory tract infections: 3C prospective cough complication cohort study
…, K Knox, A van den Bruel, M Lown… - European respiratory …, 2017 - Eur Respiratory Soc
The aim was to aid diagnosis of pneumonia in those presenting with lower respiratory tract
symptoms in routine primary care. A cohort of 28 883 adult patients with acute cough …
symptoms in routine primary care. A cohort of 28 883 adult patients with acute cough …
[HTML][HTML] Machine learning detection of Atrial Fibrillation using wearable technology
Background Atrial Fibrillation is the most common arrhythmia worldwide with a global age
adjusted prevalence of 0.5% in 2010. Anticoagulation treatment using warfarin or direct oral …
adjusted prevalence of 0.5% in 2010. Anticoagulation treatment using warfarin or direct oral …
[HTML][HTML] Mulberry-extract improves glucose tolerance and decreases insulin concentrations in normoglycaemic adults: Results of a randomised double-blind placebo …
M Lown, R Fuller, H Lightowler, A Fraser, A Gallagher… - PLoS …, 2017 - journals.plos.org
Background High sugar and refined carbohydrate intake is associated with weight gain,
increased incidence of diabetes and is linked with increased cardiovascular mortality. Reducing …
increased incidence of diabetes and is linked with increased cardiovascular mortality. Reducing …
Generalizability of blood pressure lowering trials to older patients: cross‐sectional analysis
JP Sheppard, M Lown, J Burt, E Temple… - Journal of the …, 2020 - Wiley Online Library
BACKGROUND/OBJECTIVES Randomized controlled trials are used to inform clinical
guidelines on the management of hypertension in older adults, but it is unclear to what extent …
guidelines on the management of hypertension in older adults, but it is unclear to what extent …
Resilience: what is it, why do we need it, and can it help us?
M Lown, G Lewith, C Simon, D Peters - British Journal of General Practice, 2015 - bjgp.org
The system is unlikely to change fast without political debate so how can we develop ‘resilience’skills
that will sustain us? Resilience involves effective adaptation, learning through …
that will sustain us? Resilience involves effective adaptation, learning through …
Association of frontal QRS-T angle–age risk score on admission electrocardiogram with mortality in patients admitted with an acute coronary syndrome
MT Lown, T Munyombwe, W Harrison, RM West… - The American journal of …, 2012 - Elsevier
Risk assessment is central to the management of acute coronary syndromes. Often, however,
assessment is not complete until the troponin concentration is available. Using 2 …
assessment is not complete until the troponin concentration is available. Using 2 …