Background Many patients with severe asthma require maintenance treatment with systemic
corticosteroids (SCSs) to control daily symptoms and prevent serious acute exacerbations, …

BACKGROUND: Despite intensive pharmacotherapy, a considerable number of patients
with severe asthma have inadequate disease control. Patients with severe asthma who …

BACKGROUND: Systemic corticosteroids are a leading cause of drug-related complications,
yet little has been done to quantify the dose-response relationship between systemic …

Objectives: Although systemic glucocorticoids (SGCs) are efficacious, their chronic use is
associated with a range of complications. Yet limited data are available about the risks …

Background: Mounting evidence indicates that out-of-pocket costs for prescription medications,
particularly among low- and middle-income patients with chronic diseases, are imposing …

Limited information is available on the clinical course of patients with severe asthma following
discontinuation of biologic treatment. Therefore, a post hoc analysis was conducted in …

Background Comorbidities can complicate the management of severe asthma; therefore,
the presence of comorbid conditions or traits often need to be considered when considering …

Background: Severe eosinophilic asthma patients are at risk of exacerbations, which are
associated with substantial costs. Mepolizumab lowers eosinophil levels and reduces …

Recipients of organ transplants are at increased risk for infection both because of
immunosuppression and because of the transfer of microbes through the donor organs. We report …

Objectives: Invasive aspergillosis (IA) is reported increasingly in non-traditional hosts, typically
patients with chronic obstructive pulmonary disease (COPD). Objectives were to describe …