Due to frequent and often severe lung affections caused by COVID-19, murine models of
acute respiratory distress syndrome (ARDS) are increasingly used in experimental lung …

E‐cigarette use has exploded in the past years, especially among young adults and smokers
desiring to quit. While concerns are mostly based on the presence of nicotine and flavors, …

Nonalcoholic fatty liver disease (NAFLD) prevails in obesity and is linked to several health
complications including dyslipidemia and atherosclerosis. How exactly NAFLD induces …

Reverse lipid transport is critical to maintain homeostasis. Smoking causes lipid accumulation
in macrophages, therefore suggesting suboptimal reverse lipid transport mechanisms. In …

Nicotinic receptor agonists decreased the infiltration of eosinophils into the lung and airways
in a mouse model of asthma. To better understand the mechanisms implicated in this anti-…

Objectives Hepatokines are proteins secreted by the liver that impact the functions of the
liver and various tissues through autocrine, paracrine, and endocrine signaling. Recently, …

Activation of nicotinic acetylcholine receptors (nAChRs) on inflammatory cells induces anti-inflammatory
effects. The intracellular mechanisms that regulate this effect are still poorly …

Cigarette smoke exposure induces inflammation marked by rapid and sustained neutrophil
infiltration, IL-1α, release and altered surfactant homeostasis. However, the extent to which …

Treatment of the cigarette smoke-associated lung diseases, such as chronic obstructive
pulmonary disease (COPD), has largely focused on broad-spectrum anti-inflammatory therapies. …

Lung dendritic cells (DCs) are divided into two major populations, which include CD103 +
XCR1 + cDC1s and CD11b + Sirpα + cDC2s. The maintenance of their relative proportions is …