User profiles for Maria Belvisi
Maria BelvisiProfessor of Respiratory Pharmacology, Imperial College London Verified email at imperial.ac.uk Cited by 23611 |
[HTML][HTML] Advances in TRP channel drug discovery: from target validation to clinical studies
AP Koivisto, MG Belvisi, R Gaudet… - Nature reviews Drug …, 2022 - nature.com
Transient receptor potential (TRP) channels are multifunctional signalling molecules with
many roles in sensory perception and cellular physiology. Therefore, it is not surprising that …
many roles in sensory perception and cellular physiology. Therefore, it is not surprising that …
Targeting the NF-κB pathway in asthma and chronic obstructive pulmonary disease
Asthma and chronic obstructive pulmonary disease are inflammatory lung disorders
responsible for significant morbidity and mortality worldwide. While the importance of allergic …
responsible for significant morbidity and mortality worldwide. While the importance of allergic …
Epigenome-wide association study in the European Prospective Investigation into Cancer and Nutrition (EPIC-Turin) identifies novel genetic loci associated with …
A single cytosine–guanine dinucleotide (CpG) site within coagulation factor II (thrombin)
receptor-like 3 (F2RL3) was recently found to be hypomethylated in peripheral blood genomic …
receptor-like 3 (F2RL3) was recently found to be hypomethylated in peripheral blood genomic …
Nitric oxide is the endogenous neurotransmitter of bronchodilator nerves in humans
MG Belvisi, CD Stretton, M Yacoub… - European journal of …, 1992 - Elsevier
In human airways, there is a prominent neural bronchodilator mechanism which is non-adrenergic.
In human tracheal segments, we have demonstrated that this response is mediated …
In human tracheal segments, we have demonstrated that this response is mediated …
[HTML][HTML] Lung-resident eosinophils represent a distinct regulatory eosinophil subset
…, L Gillet, M Thiry, MG Belvisi… - The Journal of …, 2016 - Am Soc Clin Investig
Increases in eosinophil numbers are associated with infection and allergic diseases, including
asthma, but there is also evidence that eosinophils contribute to homeostatic immune …
asthma, but there is also evidence that eosinophils contribute to homeostatic immune …
Expert opinion on the cough hypersensitivity syndrome in respiratory medicine
AH Morice, E Millqvist, MG Belvisi… - European …, 2014 - Eur Respiratory Soc
In 2011, a European Respiratory Society Task Force embarked on a process to determine
the position and clinical relevance of the cough hypersensitivity syndrome, a disorder …
the position and clinical relevance of the cough hypersensitivity syndrome, a disorder …
[HTML][HTML] Expression profiling in vivo demonstrates rapid changes in lung microRNA levels following lipopolysaccharide-induced inflammation but not in the anti …
Background At present, nothing is known of the role of miRNAs in the immune response in
vivo despite the fact that inflammation is thought to underlie multiple acute and chronic …
vivo despite the fact that inflammation is thought to underlie multiple acute and chronic …
[HTML][HTML] Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium
…, A Sykes, S Dahdaleh, DL Clarke, MG Belvisi… - PLoS …, 2010 - journals.plos.org
The relative roles of the endosomal TLR3/7/8 versus the intracellular RNA helicases RIG-I
and MDA5 in viral infection is much debated. We investigated the roles of each pattern …
and MDA5 in viral infection is much debated. We investigated the roles of each pattern …
Bradykinin–evoked sensitization of airway sensory nerves: A mechanism for ACE–inhibitor cough
AJ Fox, UG Lalloo, MG Belvisi, M Bernareggi… - Nature medicine, 1996 - nature.com
Cough accompanied by an increased sensitivity of the cough reflex is the most common
symptom of inflammatory airway disease 1,5 . This symptom is also frequently reported in …
symptom of inflammatory airway disease 1,5 . This symptom is also frequently reported in …
TRPA1 agonists evoke coughing in guinea pig and human volunteers
Rationale: Cough is the most frequent reason for consultation with a family doctor, or with a
general or respiratory physician. Treatment options are limited and one meta-analysis …
general or respiratory physician. Treatment options are limited and one meta-analysis …