Parkinson's disease (PD) is a major neurodegenerative chronic disease, most likely caused
by a complex interplay of genetic and environmental factors. Information on various aspects …

… Ostaszewski, M. et al. Community-driven roadmap for integrated disease maps. … Marek
Ostaszewski, Alexander Mazein, Rudi Balling & Reinhard Schneider … Marek Ostaszewski …

Background Identification of those at risk of more severe psoriasis and/or associated
morbidities offers opportunity for early intervention, reduced disease burden and more cost‐…

The development of computational approaches in systems biology has reached a state of
maturity that allows their transition to systems medicine. Despite this progress, intuitive …

We need to effectively combine the knowledge from surging literature with complex datasets
to propose mechanistic models of SARS‐CoV‐2 infection, improving data interpretation and …

The human gut microbiome produces a functional complex of biomolecules, including
nucleic acids, (poly)peptides, structural molecules, and metabolites. This impacts human …

Our growing knowledge about various molecular mechanisms is becoming increasingly
more structured and accessible. Different repositories of molecular interactions and available …

A key pathological process in Parkinson's disease (PD) is the transneuronal spreading of α‐synuclein.
Alpha‐synuclein (α‐syn) is a presynaptic protein that, in PD, forms pathological …

The Disease Maps Project builds on a network of scientific and clinical groups that exchange
best practices, share information and develop systems biomedicine tools. The project aims …

Molecular mechanisms of health and disease are often represented as systems biology
diagrams, and the coverage of such representation constantly increases. These static diagrams …