A pulmonary hypertension (PH) registry (Spanish Registry of Pulmonary Arterial Hypertension)
was undertaken to analyse prevalence, incidence and survival of pulmonary arterial …

OBJECTIVE: To investigate the incidence of clinical and immunological characteristics of a
large cohort of Spanish patients with scleroderma (SSc) and identifying factors associated …

Systemic sclerosis (SSc) is a rare, multisystem disease showing a large individual variability
in disease progression and prognosis. In the present study, we assess survival, causes of …

Systemic lupus erythematosus ( SLE ) is an autoimmune disorder characterized by the
production of antinuclear autoantibodies. In addition, the involvement of CD 4+ T‐helper (Th) …

Objective Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease with
limited reliable diagnostic biomarkers. We investigated whether gene methylation could meet …

Background Genomewide association studies of autoimmune diseases have mapped hundreds
of susceptibility regions in the genome. However, only for a few association signals has …

Introduction The purpose of this observational study was to analyze the rates, characteristics
and associated risk factors of severe infections in patients with systemic autoimmune …

Introduction According to genome wide association (GWA) studies as well as candidate
gene approaches, Behçet’s disease (BD) is associated with human leukocyte antigen (HLA)-A …

The objective of the study is to determine the importance of the mode of onset as prognostic
factor in systemic sclerosis (SSc). Data were collected from the Spanish Scleroderma …

A pesar de los avances en el tratamiento de los pacientes con hipertensión arterial pulmonar
(HAP), su supervivencia sigue estando muy afectada. El imatinib, un antagonista del factor …