Current arterial pulse monitoring systems capture data at high frequencies (100–1000 Hz).
However, they typically report averaged or low frequency summary data such as heart rate …

Vascular aging (VA) involves structural and functional changes in blood vessels that contribute
to cardiovascular disease. Several noninvasive pulse wave (PW) indices have been …

Asymmetric dimethylarginine (ADMA) and monomethyl arginine (L-NMMA) are endogenously
produced amino acids that inhibit all three isoforms of nitric oxide synthase (NOS) 1 . …

Asymmetric dimethylarginine (ADMA) — a naturally occurring amino acid that is a product of
protein breakdown — is released into the cytoplasm following the post-translational …

Classical activation of macrophages (M(LPS+IFNγ)) elicits the expression of inducible nitric
oxide synthase (iNOS), generating large amounts of NO and inhibiting mitochondrial …

Background Reliable measurement of blood pressure in conscious mice is essential in
cardiovascular research. Telemetry, the “gold‐standard” technique, is invasive and expensive …

Background: Research into the therapeutic potential of α-calcitonin gene–related peptide (α-CGRP)
has been limited because of its peptide nature and short half-life. Here, we evaluate …

Obesity induced by Western diets is associated with type 2 diabetes mellitus and cardiovascular
diseases, although underlying mechanisms are unclear. We investigated a murine …

This report aims to facilitate the implementation of the Three Rs (replacement, reduction, and
refinement) in the use of animal models or procedures involving sepsis and septic shock, …

Platelets have been implicated in pulmonary inflammatory cell recruitment after exposure to
allergic and nonallergic stimuli, but little is known about the role of platelets in response to …