Chronic inflammatory diseases are debilitating, affect patients’ quality of life, and are a
significant financial burden on health care. Inflammation is regulated by pro-inflammatory …

Gene profiling studies of patients with chronic lymphocytic leukemia (CLL) has revealed
increased expression of Ror1, a cell surface receptor tyrosine kinase. The aim of present study …

In pulmonary sarcoidosis, CD4 + T-cells expressing T-cell receptor Vα2.3 accumulate in the
lungs of HLA-DRB1*03 + patients. To investigate T-cell receptor-HLA-DRB1*03 interactions …

Background: The ectopic expression of receptor tyrosine kinase Ror1 has been reported in
patients with hematological malignancies such as chronic lymphocytic leukemia and acute …

Mucosal epithelial cell integrity is an important component of innate immunity and it protects
the host from an environment rich in microorganisms. Virulence factors from Gram-negative …

Sarcoidosis is a granulomatous disease of unknown aetiology, mainly affecting the lungs.
Recently, T-cell responses towards a specific mycobacterial protein, catalase–peroxidase (…

Proline/arginine-rich end leucine-rich repeat protein (PRELP) belongs to the small leucine-rich
proteoglycan (SLRP) family, normally expressed in extracellular matrix of collagen-rich …

Universal vaccination of neonates and children against diphtheria, tetanus and pertussis
has had a tremendous impact on the control of these infectious diseases worldwide. …

To develop an efficient dendritic cell (DC)-based immunotherapy protocol, we examined
whether simultaneous pulsing of DCs with a given antigen and a third-party antigen could …

Problem Recurrent spontaneous abortion (RSA) is a relatively common disorder, the
underlying causes of which are thought to be immunological in most cases. Method of study …