COL4A3 is degraded in allergic asthma and degradation predicts response to anti-IgE therapy

…, C Happle, KF Rabe, M van de Berge… - European …, 2021 - Eur Respiratory Soc
Background Asthma is a heterogeneous syndrome substantiating the urgent requirement for
endotype-specific biomarkers. Dysbalance of fibrosis and fibrolysis in asthmatic lung tissue …

[HTML][HTML] Clinical significance and applications of oscillometry

…, PD Robinson, M Van den Berge… - European respiratory …, 2022 - Eur Respiratory Soc
Recently, “Technical standards for respiratory oscillometry” was published, which reviewed
the physiological basis of oscillometric measures and detailed the technical factors related to …

[HTML][HTML] Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years …

…, F Tavakoli, M Toizumi, N Tsedenbal, M van den Berge… - The Lancet, 2022 - thelancet.com
Background Respiratory syncytial virus (RSV) is the most common cause of acute lower
respiratory infection in young children. We previously estimated that in 2015, 33ˇ1 million …

[HTML][HTML] Glutathione S-transferases and their implications in the lung diseases asthma and chronic obstructive pulmonary disease: Early life susceptibility?

…, M Berg, CHJ Schiffers, V Stylianidis, M van den Berge… - Redox Biology, 2021 - Elsevier
Our lungs are exposed daily to airborne pollutants, particulate matter, pathogens as well as
lung allergens and irritants. Exposure to these substances can lead to inflammatory …

The burden of respiratory syncytial virus in healthy term-born infants in Europe: a prospective birth cohort study

…, A Meijer, TK Fischer, M van den Berge… - The Lancet …, 2023 - thelancet.com
Background Respiratory syncytial virus (RSV) is a major cause of hospitalisation in infants.
The burden of RSV infection in healthy term infants has not yet been established. Accurate …

Technical standards for respiratory oscillometry

…, C Thamrin, M van den Berge… - European …, 2020 - Eur Respiratory Soc
Oscillometry (also known as the forced oscillation technique) measures the mechanical
properties of the respiratory system (upper and intrathoracic airways, lung tissue and chest wall) …

[HTML][HTML] Resveratrol and pterostilbene inhibit SARS-CoV-2 replication in air–liquid interface cultured human primary bronchial epithelial cells

…, L Apperloo, D van Gosliga, M van den Berge… - Viruses, 2021 - mdpi.com
The current COVID-19 pandemic is caused by severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) and has an enormous impact on human health and economy. In search …

[PDF][PDF] SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues

…, S Teichmann, F Theis, A Tsankov, M van den Berge… - Cell, 2020 - cell.com
There is pressing urgency to understand the pathogenesis of the severe acute respiratory
syndrome coronavirus clade 2 (SARS-CoV-2), which causes the disease COVID-19. SARS-…

[HTML][HTML] An integrated cell atlas of the lung in health and disease

…, M van den Berge… - Nature Medicine, 2023 - nature.com
Single-cell technologies have transformed our understanding of human tissues. Yet, studies
typically capture only a limited number of donors and disagree on cell type definitions. …

PC20 Adenosine 5 ′ -Monophosphate Is More Closely Associated with Airway Inflammation in Asthma Than PC20 Methacholine

M Van Den BERGE, RJ MEIJER… - American Journal of …, 2001 - atsjournals.org
Inhalation of a direct stimulus such as histamine or methacholine is generally used to
measure bronchial hyperresponsiveness (BHR). Provocation with adenosine 5 ′ -…