Background We have previously estimated that respiratory syncytial virus (RSV) was associated
with 22% of all episodes of (severe) acute lower respiratory infection (ALRI) resulting in …

… SD Lawn and MP Nicol are both funded by the Wellcome Trust, London, UK, and MP Nicol
has also received funding from EDCTP and the NIH (USA). MP Nicol has received funding …

Background Respiratory syncytial virus (RSV) is the most common cause of acute lower
respiratory infection in young children. We previously estimated that in 2015, 33·1 million …

Background Global control of tuberculosis is hampered by slow, insensitive diagnostic
methods, particularly for the detection of drug-resistant forms and in patients with human …

Background The Xpert MTB/RIF test (Cepheid, Sunnyvale, CA, USA) can detect tuberculosis
and its multidrug-resistant form with very high sensitivity and specificity in controlled studies, …

… Zar HJ, Workman L, Nicol MP. Diagnosis of pulmonary tuberculosis in HIV-infected and
uninfected children using Xpert MTB/RIF Ultra. International Conference of the American …

Background WHO recommends that Xpert MTB/RIF replaces smear microscopy for initial
diagnosis of suspected HIV-associated tuberculosis or multidrug-resistant pulmonary …

Background Xpert MTB/RIF (Xpert) is a promising new rapid diagnostic technology for
tuberculosis (TB) that has characteristics that suggest large-scale roll-out. However, because the …

… The authors declare that the University of Cape Town (Mark Nicol as Principal Investigator)
has received research funding from FIND to conduct research around the evaluation and …

Background Influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus
are the most common viruses associated with acute lower respiratory infections in …