Acute respiratory distress syndrome (ARDS) is a heterogeneous clinical syndrome. Understanding
of the complex pathways involved in lung injury pathogenesis, resolution, and repair …

Clinical and pathophysiological understanding of septic shock has progressed
exponentially in the previous decades, translating into a steady decrease in septic shock-related …

Objectives: Recently, many studies have investigated the immunomodulatory effects of
insulin and glucose control in critical illness. This review examines evidence regarding the …

Background The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
the cause of a rapidly spreading illness, Coronavirus Disease 2019 (COVID-19), affecting …

… Dr Gong reported receiving grants from CDC during the conduct of the study; grants from
NIH to conduct clinical trials on COVID-19 and non–COVID-19 outside the submitted work; and …

Objectives To characterize the clinical severity of covid-19 associated with the alpha, delta,
and omicron SARS-CoV-2 variants among adults admitted to hospital and to compare the …

Introduction Acute kidney injury (AKI) can evolve quickly and clinical measures of function
often fail to detect AKI at a time when interventions are likely to provide benefit. Identifying …

… Dr Gong reported receiving grants from the NHLBI for the submitted work and research
funding from the Agency for Healthcare Research and Quality and Regeneron outside the …

BACKGROUND: The coronavirus disease 2019 pandemic continues to affect millions worldwide.
Given the rapidly growing evidence base, we implemented a living guideline model to …

Background Vasodilatory shock that does not respond to high-dose vasopressors is associated
with high mortality. We investigated the effectiveness of angiotensin II for the treatment of …