[HTML][HTML] Explaining the user experience of recommender systems
Research on recommender systems typically focuses on the accuracy of prediction algorithms.
Because accuracy only partially constitutes the user experience of a recommender system…
Because accuracy only partially constitutes the user experience of a recommender system…
Meta-analysis of 2,104 trios provides support for 10 new genes for intellectual disability
…, P de Vries, BBA de Vries, MH Willemsen… - Nature …, 2016 - nature.com
To identify candidate genes for intellectual disability, we performed a meta-analysis on
2,637 de novo mutations, identified from the exomes of 2,104 patient–parent trios. Statistical …
2,637 de novo mutations, identified from the exomes of 2,104 patient–parent trios. Statistical …
Predicting expatriate job performance for selection purposes: A quantitative review
This article meta-analytically reviews empirical studies on the prediction of expatriate job
performance. Using 30 primary studies (total N = 4,046), it was found that predictive validities of …
performance. Using 30 primary studies (total N = 4,046), it was found that predictive validities of …
[HTML][HTML] Diagnostic exome sequencing in persons with severe intellectual disability
J De Ligt, MH Willemsen, BWM Van Bon… - … England Journal of …, 2012 - Mass Medical Soc
Background The causes of intellectual disability remain largely unknown because of
extensive clinical and genetic heterogeneity. Methods We evaluated patients with intellectual …
extensive clinical and genetic heterogeneity. Methods We evaluated patients with intellectual …
Genome sequencing identifies major causes of severe intellectual disability
…, M Van De Vorst, BWM Van Bon, MH Willemsen… - Nature, 2014 - nature.com
Severe intellectual disability (ID) occurs in 0.5% of newborns and is thought to be largely
genetic in origin 1 , 2 . The extensive genetic heterogeneity of this disorder requires a genome-…
genetic in origin 1 , 2 . The extensive genetic heterogeneity of this disorder requires a genome-…
Prospective assessment of falls in Parkinson's disease
…, YAM Grimbergen, M Cramer, M Willemsen… - Journal of …, 2001 - Springer
We studied prospectively the epidemiology, clinical impact and prediction of falls in 59
moderately affected patients with Parkinson's disease (PD) (mean UPDRS motor score 31.5; …
moderately affected patients with Parkinson's disease (PD) (mean UPDRS motor score 31.5; …
Understanding the factors that promote employability orientation: the impact of employability culture, career satisfaction, and role breadth self‐efficacy
…, K Van Dam, M Willemsen - … of occupational and …, 2009 - Wiley Online Library
This study among 702 Dutch employees working in the health care and welfare sector
examined individual and organizational factors that are related to workers' employability …
examined individual and organizational factors that are related to workers' employability …
Mutations in antiquitin in individuals with pyridoxine-dependent seizures
…, P Baxter, M Baumgartner, MAAP Willemsen… - Nature medicine, 2006 - nature.com
We show here that children with pyridoxine-dependent seizures (PDS) have mutations in the
ALDH7A1 gene, which encodes antiquitin; these mutations abolish the activity of antiquitin …
ALDH7A1 gene, which encodes antiquitin; these mutations abolish the activity of antiquitin …
Structure-dependent, competitive interaction of hydroxy-polychlorobiphenyls,-dibenzo-p-dioxins and-dibenzofurans with human transthyretin
MC Lans, E Klasson-Wehler, M Willemsen… - Chemico-biological …, 1993 - Elsevier
Previous results from our laboratory indicated specific and competitive interactions of
hydroxylated metabolites of 3,3′,4,4′-tetrachlorobiphenyl with the plasma thyroid hormone …
hydroxylated metabolites of 3,3′,4,4′-tetrachlorobiphenyl with the plasma thyroid hormone …
[PDF][PDF] Clinical and molecular phenotype of Aicardi-Goutieres syndrome
…, B Weschke, ML Whiteford, MAA Willemsen… - The American Journal of …, 2007 - cell.com
Aicardi-Goutières syndrome (AGS) is a genetic encephalopathy whose clinical features mimic
those of acquired in utero viral infection. AGS exhibits locus heterogeneity, with mutations …
those of acquired in utero viral infection. AGS exhibits locus heterogeneity, with mutations …