[HTML][HTML] The infant nasopharyngeal microbiome impacts severity of lower respiratory infection and risk of asthma development
The nasopharynx (NP) is a reservoir for microbes associated with acute respiratory
infections (ARIs). Lung inflammation resulting from ARIs during infancy is linked to asthma …
infections (ARIs). Lung inflammation resulting from ARIs during infancy is linked to asthma …
Maternal serum vitamin D levels during pregnancy and offspring neurocognitive development
AJO Whitehouse, BJ Holt, M Serralha, PG Holt… - …, 2012 - publications.aap.org
… Drs Whitehouse, Kusel, and Hart developed the hypotheses; Ms Holt, Mr Serralha, Dr Holt,
and Dr Hart analyzed serum samples for 25(OH)-vitamin D concentrations; and Dr …
and Dr Hart analyzed serum samples for 25(OH)-vitamin D concentrations; and Dr …
An immunoepidemiological approach to asthma: identification of in-vitro T cell response patterns associated with different wheezing phenotypes in children
…, N De Klerk, D Suriyaarachchi, M Serralha… - The Lancet, 2005 - thelancet.com
Background Increasing evidence suggests that patterns of T cell immunity to inhalant
allergens in genetically diverse human populations are more heterogeneous than previously …
allergens in genetically diverse human populations are more heterogeneous than previously …
Vitamin D and atopy and asthma phenotypes in children: a longitudinal cohort study
…, PH Hart, BJ Holt, M Serralha… - European …, 2011 - Eur Respiratory Soc
Vitamin D has been linked in some studies with atopy- and asthma-associated phenotypes in
children with established disease, but its role in disease inception at the community level is …
children with established disease, but its role in disease inception at the community level is …
[PDF][PDF] Airway microbiota dynamics uncover a critical window for interplay of pathogenic bacteria and allergy in childhood respiratory disease
…, SC Watts, K Pham, BJ Holt, M Kusel, M Serralha… - Cell host & …, 2018 - cell.com
Repeated cycles of infection-associated lower airway inflammation drive the pathogenesis
of persistent wheezing disease in children. In this study, the occurrence of acute respiratory …
of persistent wheezing disease in children. In this study, the occurrence of acute respiratory …
Low maternal serum vitamin D during pregnancy and the risk for postpartum depression symptoms
Pregnancy is a time of vulnerability for vitamin D insufficiency, and there is an emerging
literature associating low levels of 25(OH)-vitamin D with depressive symptoms. However, the …
literature associating low levels of 25(OH)-vitamin D with depressive symptoms. However, the …
Toward improved prediction of risk for atopy and asthma among preschoolers: a prospective cohort study
…, K McKenna, L Subrata, N De Klerk, M Serralha… - Journal of Allergy and …, 2010 - Elsevier
BACKGROUND: Atopy and asthma are commonly initiated during early life, and there is
increasing interest in the development of preventive treatments for at-risk children. However, …
increasing interest in the development of preventive treatments for at-risk children. However, …
Fish oil supplementation in early infancy modulates developing infant immune responses
…, J Metcalfe, BJ Holt, M Serralha… - Clinical & …, 2012 - Wiley Online Library
Background Maternal fish oil supplementation during pregnancy has been associated with
altered infant immune responses and a reduced risk of infant sensitization and eczema. …
altered infant immune responses and a reduced risk of infant sensitization and eczema. …
Maternal vitamin D levels and the autism phenotype among offspring
AJO Whitehouse, BJ Holt, M Serralha, PG Holt… - Journal of autism and …, 2013 - Springer
… during the summer (M = 67.32 nmol/L, SD = 20.17 nmol/L) and autumn (M = 64.36 nmol/L, …
collected during the winter (M = 50.60 nmol/L, SD = 17.74 nmol/L) and spring (M = 54.29 nmol/…
collected during the winter (M = 50.60 nmol/L, SD = 17.74 nmol/L) and spring (M = 54.29 nmol/…
Prenatal versus postnatal sensitization to environmental allergens in a high-risk birth cohort
…, M Kusel, BJ Holt, D Suriyaarachchi, M Serralha… - Journal of allergy and …, 2007 - Elsevier
BACKGROUND: The timing of allergen sensitization is controversial, with conflicting evidence
suggesting transplacental priming versus exclusively postnatal priming. Resolution of this …
suggesting transplacental priming versus exclusively postnatal priming. Resolution of this …