User profiles for M. Kristen Demoruelle
Kristen DemoruelleUniversity of Colorado, Anschutz Medical Campus Verified email at ucdenver.edu Cited by 4287 |
Genetic and environmental risk factors for rheumatoid arthritis
KD Deane, MK Demoruelle, LB Kelmenson… - Best practice & research …, 2017 - Elsevier
Multiple genetic and environmental factors have been associated with an increased risk for
rheumatoid arthritis (RA). Of these, the strongest associations have been seen with female …
rheumatoid arthritis (RA). Of these, the strongest associations have been seen with female …
Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum
…, S Liu, MD Maerz, DN Frank, MK Demoruelle… - Science translational …, 2022 - science.org
The mucosal origins hypothesis of rheumatoid arthritis (RA) proposes a central role for
mucosal immune responses in the initiation or perpetuation of the systemic autoimmunity that …
mucosal immune responses in the initiation or perpetuation of the systemic autoimmunity that …
Predictors of mortality in rheumatoid arthritis-associated interstitial lung disease
…, GP Cosgrove, MK Demoruelle… - European …, 2016 - Eur Respiratory Soc
Interstitial lung disease (ILD) is a common pulmonary manifestation of rheumatoid arthritis.
There is lack of clarity around predictors of mortality and disease behaviour over time in these …
There is lack of clarity around predictors of mortality and disease behaviour over time in these …
Brief Report: Airways abnormalities and rheumatoid arthritis–related autoantibodies in subjects without arthritis: Early injury or initiating site of autoimmunity?
MK Demoruelle, MH Weisman… - Arthritis & …, 2012 - Wiley Online Library
Objective To evaluate the presence of pulmonary abnormalities in rheumatoid arthritis (RA)–related
autoantibody–positive subjects without inflammatory arthritis. Methods Forty‐two …
autoantibody–positive subjects without inflammatory arthritis. Methods Forty‐two …
Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction
VM Holers, MK Demoruelle, KA Kuhn… - Nature Reviews …, 2018 - nature.com
Individuals at high risk of developing seropositive rheumatoid arthritis (RA) can be identified
for translational research and disease prevention studies through the presence of highly …
for translational research and disease prevention studies through the presence of highly …
Sputum autoantibodies in patients with established rheumatoid arthritis and subjects at risk of future clinically apparent disease
VC Willis, MK Demoruelle, LA Derber… - Arthritis & …, 2013 - Wiley Online Library
Objective To evaluate the generation of rheumatoid arthritis (RA)–related autoantibodies in
the lung. Methods Simultaneous collection of serum and induced sputum was performed in …
the lung. Methods Simultaneous collection of serum and induced sputum was performed in …
When and where does inflammation begin in rheumatoid arthritis?
MK Demoruelle, KD Deane… - Current opinion in …, 2014 - journals.lww.com
Investigations are needed to determine when and where RA begins, including comprehensive
prospective studies of individuals in the preclinical period of RA that can provide insight …
prospective studies of individuals in the preclinical period of RA that can provide insight …
Anti-carbamylated protein antibodies are present prior to rheumatoid arthritis and are associated with its future diagnosis
Objective. Anti-carbamylated protein (anti-CarP) antibodies could further elucidate early
rheumatoid arthritis (RA) pathogenesis and predict clinical disease. We compared the …
rheumatoid arthritis (RA) pathogenesis and predict clinical disease. We compared the …
Treatment strategies in early rheumatoid arthritis and prevention of rheumatoid arthritis
MK Demoruelle, KD Deane - Current rheumatology reports, 2012 - Springer
Data now suggest that current strategies in the treatment of rheumatoid arthritis (RA) should
focus on early identification and diagnosis, followed by early initiation of DMARD therapy. …
focus on early identification and diagnosis, followed by early initiation of DMARD therapy. …
Anti–citrullinated protein antibodies are associated with neutrophil extracellular traps in the sputum in relatives of rheumatoid arthritis patients
MK Demoruelle, KK Harrall, L Ho… - Arthritis & …, 2017 - Wiley Online Library
Objective Studies suggest that rheumatoid arthritis (RA)–related autoimmunity is initiated at
a mucosal site. However, the factors associated with the mucosal generation of this …
a mucosal site. However, the factors associated with the mucosal generation of this …