Challenges in measuring and understanding biological noise
N Eling, MD Morgan, JC Marioni - Nature Reviews Genetics, 2019 - nature.com
… Morgan and Marioni 13 further distinguished between genes controlled by promoters
associated with short and long CGIs. Similarly to the presence of TATA box motifs, the length of …
associated with short and long CGIs. Similarly to the presence of TATA box motifs, the length of …
[HTML][HTML] Rituximab versus cyclophosphamide in ANCA-associated renal vasculitis
…, T Hauser, R Luqmani, MD Morgan… - … England Journal of …, 2010 - Mass Medical Soc
Background Cyclophosphamide induction regimens for antineutrophil cytoplasmic antibody
(ANCA)–associated vasculitis are effective in 70 to 90% of patients, but they are associated …
(ANCA)–associated vasculitis are effective in 70 to 90% of patients, but they are associated …
Development of a shuttle walking test of disability in patients with chronic airways obstruction.
SJ Singh, MD Morgan, S Scott, D Walters, AE Hardman - Thorax, 1992 - thorax.bmj.com
BACKGROUND: The aim was to develop a standardised and externally paced field walking
test, incorporating an incremental and progressive structure, to assess functional capacity in …
test, incorporating an incremental and progressive structure, to assess functional capacity in …
Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors
Large-scale single-cell RNA sequencing (scRNA-seq) data sets that are produced in
different laboratories and at different times contain batch effects that may compromise the …
different laboratories and at different times contain batch effects that may compromise the …
[HTML][HTML] Single-cell multi-omics analysis of the immune response in COVID-19
Abstract Analysis of human blood immune cells provides insights into the coordinated
response to viral infections such as severe acute respiratory syndrome coronavirus 2, which …
response to viral infections such as severe acute respiratory syndrome coronavirus 2, which …
British Thoracic Society guideline on pulmonary rehabilitation in adults: accredited by NICE
Aim Pulmonary rehabilitation has established itself as a key management strategy in people
with chronic respiratory disease. The role of pulmonary rehabilitation has recently been …
with chronic respiratory disease. The role of pulmonary rehabilitation has recently been …
[PDF][PDF] Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease
The kinetics of the immune changes in COVID-19 across severity groups have not been
rigorously assessed. Using immunophenotyping, RNA sequencing, and serum cytokine analysis…
rigorously assessed. Using immunophenotyping, RNA sequencing, and serum cytokine analysis…
Comparison of oxygen uptake during a conventional treadmill test and the shuttle walking test in chronic airflow limitation
SJ Singh, MD Morgan, AE Hardman… - European …, 1994 - Eur Respiratory Soc
The purpose of this study was to investigate the relationship between performance on the
shuttle walking test and maximal oxygen uptake (VO2max) during a conventional treadmill test …
shuttle walking test and maximal oxygen uptake (VO2max) during a conventional treadmill test …
Differential abundance testing on single-cell data using k-nearest neighbor graphs
Current computational workflows for comparative analyses of single-cell datasets typically
use discrete clusters as input when testing for differential abundance among experimental …
use discrete clusters as input when testing for differential abundance among experimental …
Pulse versus daily oral cyclophosphamide for induction of remission in ANCA-associated vasculitis: long-term follow-up
Introduction The previously reported randomised controlled trial of a consensus regimen of
pulse cyclophosphamide suggested that it was as effective as a daily oral (DO) …
pulse cyclophosphamide suggested that it was as effective as a daily oral (DO) …