Background A small proportion of patients with chronic myeloproliferative diseases have
constitutive activation of the gene for platelet-derived growth factor receptor beta (PDGFRB), …

Background/Aims: A recent NIH research workshop on hepatitis B virus (HBV) revisited the
definition of healthy HBsAg carriers. The new definition inactive surface antigen (HBsAg) …

Ten percent of patients who undergo resection for hepatocellular carcinoma (HCC) associated
with chronic liver disease have no detectable cause for this underlying liver disease. …

Erdheim-Chester disease (ECD) is a rare histiocytic disorder that is challenging to diagnose
and treat. We performed molecular analysis of BRAF in the largest cohort of ECD patients …

In patients presenting with idiopathic pulmonary fibrosis (IPF), modifications of pulmonary
vessels are well defined in fibrotic areas but have not been accurately assessed in the …

Light chain deposition disease (LCDD) is a rare disorder that very uncommonly affects the
lung. We report three cases of severe cystic pulmonary LCDD leading to lung transplantation. …

… Eculizumab use was associated with significant improvement in kidney function, with
estimated glomerular filtration rates of patients increasing 22 to 38 mL/min/1.73 m 2 . Eculizumab …

… in all patients, nephrotic range proteinuria in 75% of patients, hypertension in 80% of patients,
and renal failure in 85% of patients (mean glomerular filtration rate, 46 mL/min per 1.73 m …

Background. Familial Mediterranean fever (FMF) is an autosomal recessive autoinflammatory
disorder, for which systemic AA amyloidosis is the major complication revealed most of the …

Background: Atrial fibrillation (AF) commonly affects patients with cardiac amyloidosis (CA).
Amyloid deposition within the left atrium may be responsible for the subtype of AF in either …